Automated detection Basic and applied research Benchmarking Computational architecture Computational methods Computational processing Computational resources Data parallelization GATK Genome High-Throughput Nucleotide Sequencing High-throughput sequencing Humans Java Next generation sequencing Next-generation sequencing Open source software Polymorphism, Single Nucleotide Reproducibility Reproducibility of Results SNP Single nucleotide polymorphisms Software Variant calling Workflow genome high throughput sequencing human indel reproducibility