Linking neuroinflammation to motor neuron degeneration in ALS: The critical role of CXCL13/CXCR5

by Alizée ARNOUX, Luc DUPUIS
Published 2021-01-01

Role of RNA Binding Proteins with prion-like domains in muscle and neuromuscular diseases

by Gina Picchiarelli, Luc Dupuis
Published 2020-03-01

Hypothalamic Alterations in Neurodegenerative Diseases and Their Relation to Abnormal Energy Metabolism

by Pauline Vercruysse, Pauline Vercruysse, Pauline Vercruysse, Didier Vieau, David Blum, Åsa Petersén, Luc Dupuis, Luc Dupuis
Published 2018-01-01

Fumaric acid esters stimulate astrocytic VEGF expression through HIF-1α and Nrf2.

by Diana Wiesner, Irma Merdian, Jan Lewerenz, Albert C Ludolph, Luc Dupuis, Anke Witting
Published 2013-01-01

Adipose Tissue Distribution Predicts Survival in Amyotrophic Lateral Sclerosis.

by Eva Lindauer, Luc Dupuis, Hans-Peter Müller, Heiko Neumann, Albert C Ludolph, Jan Kassubek
Published 2013-01-01

Adipokines, C-reactive protein and Amyotrophic Lateral Sclerosis – results from a population- based ALS registry in Germany

by Gabriele Nagel, Raphael S. Peter, Angela Rosenbohm, Wolfgang Koenig, Luc Dupuis, Dietrich Rothenbacher, Albert C. Ludolph
Published 2017-06-01

Differential Screening of Mutated SOD1 Transgenic Mice Reveals Early Up-Regulation of a Fast Axonal Transport Component in Spinal Cord Motor Neurons

by Luc Dupuis, Marc de Tapia, Frédérique René, Bernadette Lutz-Bucher, Jon W. Gordon, Luc Mercken, Laurent Pradier, Jean-Philippe Loeffler
Published 2000-08-01

Antibody-bound β-amyloid precursor protein stimulates the production of tumor necrosis factor-α and monocyte chemoattractant protein-1 by cortical neurons

by Corinne Mbebi, Jose-Luis González de Aguilar, Violaine Sée, Luc Dupuis, Nelly Frossard, Luc Mercken, Laurent Pradier, Yves Larmet, Jean-Philippe Loeffler
Published 2005-06-01

Platelet serotonin level predicts survival in amyotrophic lateral sclerosis.

by Luc Dupuis, Odile Spreux-Varoquaux, Gilbert Bensimon, Philippe Jullien, Lucette Lacomblez, François Salachas, Gaëlle Bruneteau, Pierre-François Pradat, Jean-Philippe Loeffler, Vincent Meininger
Published 2010-10-01

Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosiss⃞

by Anissa Fergani, Hugues Oudart, Jose-Luis Gonzalez De Aguilar, Bastien Fricker, Frédérique René, Jean-François Hocquette, Vincent Meininger, Luc Dupuis, Jean-Philippe Loeffler
Published 2007-07-01

Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients

by David Bayer, Stefano Antonucci, Hans-Peter Müller, Rami Saad, Luc Dupuis, Volker Rasche, Tobias M. Böckers, Albert C. Ludolph, Jan Kassubek, Francesco Roselli
Published 2021-05-01

VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans.

by Sung Min Han, Hajer El Oussini, Jelena Scekic-Zahirovic, Jack Vibbert, Pauline Cottee, Jeevan K Prasain, Hugo J Bellen, Luc Dupuis, Michael A Miller
Published 2013-01-01

Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons.

by Luc Dupuis, Jose-Luis Gonzalez de Aguilar, Andoni Echaniz-Laguna, Judith Eschbach, Frédérique Rene, Hugues Oudart, Benoit Halter, Caroline Huze, Laurent Schaeffer, Frédéric Bouillaud, Jean-Philippe Loeffler
Published 2009-01-01

Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS

by Sonu Sahadevan, Katharina M. Hembach, Elena Tantardini, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Salim Megat, Julien Weber, Petra Schwarz, Luc Dupuis, Mark D. Robinson, Pierre De Rossi, Magdalini Polymenidou
Published 2021-05-01

Nogo Provides a Molecular Marker for Diagnosis of Amyotrophic Lateral Sclerosis

by Luc Dupuis, Jose-Luis Gonzalez de Aguilar, Franck di Scala, Frédérique Rene, Marc de Tapia, Pierre-François Pradat, Lucette Lacomblez, Danielle Seihlan, Rabinder Prinjha, Frank S. Walsh, Vincent Meininger, Jean-Philippe Loeffler
Published 2002-08-01

Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury.

by Ghulam Hussain, Florent Schmitt, Alexandre Henriques, Thiebault Lequeu, Frederique Rene, Françoise Bindler, Sylvie Dirrig-Grosch, Hugues Oudart, Lavinia Palamiuc, Marie-Helene Metz-Boutigue, Luc Dupuis, Eric Marchioni, Jose-Luis Gonzalez De Aguilar, Jean-Philippe Loeffler
Published 2013-01-01

ALS-causing mutations differentially affect PGC-1α expression and function in the brain vs. peripheral tissues

by Hanna Bayer, Kerstin Lang, Eva Buck, Julia Higelin, Lara Barteczko, Noemi Pasquarelli, Jasmin Sprissler, Tanja Lucas, Karlheinz Holzmann, Maria Demestre, Katrin S. Lindenberg, Karin M. Danzer, Tobias Boeckers, Albert C. Ludolph, Luc Dupuis, Patrick Weydt, Anke Witting
Published 2017-01-01

Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation

by Inmaculada Sanjuan-Ruiz, Noé Govea-Perez, Melissa McAlonis-Downes, Stéphane Dieterle, Salim Megat, Sylvie Dirrig-Grosch, Gina Picchiarelli, Diana Piol, Qiang Zhu, Brian Myers, Chao-Zong Lee, Don W Cleveland, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Luc Dupuis
Published 2021-09-01

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

by Júlia Canet-Pons, Nesli-Ece Sen, Aleksandar Arsović, Luis-Enrique Almaguer-Mederos, Melanie V. Halbach, Jana Key, Claudia Döring, Anja Kerksiek, Gina Picchiarelli, Raphaelle Cassel, Frédérique René, Stéphane Dieterlé, Nina V. Fuchs, Renate König, Luc Dupuis, Dieter Lütjohann, Suzana Gispert, Georg Auburger
Published 2021-05-01

Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age

by Judith Eschbach, Jérôme Sinniger, Jamal Bouitbir, Anissa Fergani, Anna-Isabel Schlagowski, Joffrey Zoll, Bernard Geny, Frédérique René, Yves Larmet, Vincent Marion, Robert H. Baloh, Matthew B. Harms, Michael E. Shy, Nadia Messadeq, Patrick Weydt, Jean-Philippe Loeffler, Albert C. Ludolph, Luc Dupuis
Published 2013-10-01