Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses

by Luděk Eyer, Radim Nencka, Erik de Clercq, Katherine Seley-Radtke, Daniel Růžek
Published 2018-03-01

Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus

by Ewelina Krol, Ilona Wandzik, Gabriela Brzuska, Luděk Eyer, Daniel Růžek, Boguslaw Szewczyk
Published 2019-03-01

Antiviral Activity of Vacuolar ATPase Blocker Diphyllin against SARS-CoV-2

by Michal Stefanik, Petra Strakova, Jan Haviernik, Andrew D. Miller, Daniel Ruzek, Ludek Eyer
Published 2021-02-01

FDA Approved Drugs Efavirenz, Tipranavir, and Dasabuvir Inhibit Replication of Multiple Flaviviruses In Vitro

by Michal Stefanik, Fortunatus C Ezebuo, Jan Haviernik, Ikemefuna C. Uzochukwu, Martina Fojtikova, Jiri Salat, Ludek Eyer, Daniel Ruzek
Published 2020-06-01

Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses

by Jan Haviernik, Michal Štefánik, Martina Fojtíková, Sabrina Kali, Noël Tordo, Ivo Rudolf, Zdeněk Hubálek, Luděk Eyer, Daniel Ruzek
Published 2018-04-01

Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication

by Milan Dejmek, Eva Konkoľová, Luděk Eyer, Petra Straková, Pavel Svoboda, Michal Šála, Kateřina Krejčová, Daniel Růžek, Evzen Boura, Radim Nencka
Published 2021-08-01

FDA-Approved Drugs Efavirenz, Tipranavir, and Dasabuvir Inhibit Replication of Multiple Flaviviruses in Vero Cells

by Michal Stefanik, James J. Valdes, Fortunatus C. Ezebuo, Jan Haviernik, Ikemefuna C. Uzochukwu, Martina Fojtikova, Jiri Salat, Ludek Eyer, Daniel Ruzek
Published 2020-04-01

An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus in Mice

by Jan Haviernik, Ludek Eyer, Antoine Nougairède, Marie Uhlířová, Jean-Sélim Driouich, Darina Zouharová, James Jason Valdés, Ernest Gould, Erik De Clercq, Xavier de Lamballerie, Daniel Ruzek
Published 2020-06-01

Characterisation of Zika virus infection in primary human astrocytes

by Michal Stefanik, Petra Formanova, Tomas Bily, Marie Vancova, Ludek Eyer, Martin Palus, Jiri Salat, Carla Torres Braconi, Paolo M. de A. Zanotto, Ernest A. Gould, Daniel Ruzek
Published 2018-02-01

Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals

by Jiri Salat, Kamil Mikulasek, Osmany Larralde, Petra Pokorna Formanova, Ales Chrdle, Jan Haviernik, Jana Elsterova, Dana Teislerova, Martin Palus, Ludek Eyer, Zbynek Zdrahal, Juraj Petrik, Daniel Ruzek
Published 2020-02-01

2,4-D and IAA Amino Acid Conjugates Show Distinct Metabolism in Arabidopsis.

by Luděk Eyer, Thomas Vain, Barbora Pařízková, Jana Oklestkova, Elke Barbez, Hana Kozubíková, Tomáš Pospíšil, Roksana Wierzbicka, Jürgen Kleine-Vehn, Milan Fránek, Miroslav Strnad, Stéphanie Robert, Ondrej Novak
Published 2016-01-01