Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme.

by Eyong Egbe, Colin W Levy, Lydia Tabernero
Published 2020-01-01

Kinetic Modeling of DUSP Regulation in Herceptin-Resistant HER2-Positive Breast Cancer

by Petronela Buiga, Ari Elson, Lydia Tabernero, Jean-Marc Schwartz
Published 2019-07-01

VSpipe, an Integrated Resource for Virtual Screening and Hit Selection: Applications to Protein Tyrosine Phospahatase Inhibition

by Sandra Álvarez-Carretero, Niki Pavlopoulou, James Adams, Jane Gilsenan, Lydia Tabernero
Published 2018-02-01

Characteristics of the First Protein Tyrosine Phosphatase with Phytase Activity from a Soil Metagenome

by Genis Andrés Castillo Villamizar, Heiko Nacke, Laura Griese, Lydia Tabernero, Katrina Funkner, Rolf Daniel
Published 2019-01-01

The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function

by Deepankar Gahloth, Graham Heaven, Thomas A. Jowitt, A. Paul Mould, Jordi Bella, Clair Baldock, Philip Woodman, Lydia Tabernero
Published 2017-08-01

Identification of Functional and Druggable Sites in <i>Aspergillus fumigatus</i> Essential Phosphatases by Virtual Screening

by Benjamin P. Thornton, Anna Johns, Reem Al-Shidhani, Sandra Álvarez-Carretero, Isabelle S. R. Storer, Michael J. Bromley, Lydia Tabernero
Published 2019-09-01

Discovery of uncompetitive inhibitors of SapM that compromise intracellular survival of Mycobacterium tuberculosis

by Paulina Fernández-Soto, Joshua Casulli, Danilo Solano-Castro, Pablo Rodríguez-Fernández, Thomas A. Jowitt, Mark A. Travis, Jennifer S. Cavet, Lydia Tabernero
Published 2021-04-01