Re-Evaluating the Effects of Obesity on Cancer Immunotherapy Outcomes in Renal Cancer: What Do We Really Know?

by Kristine I. Farag, Amani Makkouk, Lyse A. Norian, Lyse A. Norian, Lyse A. Norian
Published 2021-08-01

Rapid maturation of effector T cells in tumors, but not lymphoid organs, during tumor regression.

by Lyse A Norian, Paul M Allen
Published 2007-09-01

Obesity-Associated Myeloid-Derived Suppressor Cells Promote Apoptosis of Tumor-Infiltrating CD8 T Cells and Immunotherapy Resistance in Breast Cancer

by Justin T. Gibson, Rachael M. Orlandella, William J. Turbitt, Michael Behring, Upender Manne, Upender Manne, Robert E. Sorge, Robert E. Sorge, Lyse A. Norian, Lyse A. Norian, Lyse A. Norian
Published 2020-10-01

Advances in Viral Vector-Based TRAIL Gene Therapy for Cancer

by Lyse A. Norian, Britnie R. James, Thomas S. Griffith
Published 2011-02-01

Targeting Glucose Metabolism to Enhance Immunotherapy: Emerging Evidence on Intermittent Fasting and Calorie Restriction Mimetics

by William J. Turbitt, William J. Turbitt, Wendy Demark-Wahnefried, Wendy Demark-Wahnefried, Wendy Demark-Wahnefried, Courtney M. Peterson, Courtney M. Peterson, Lyse A. Norian, Lyse A. Norian, Lyse A. Norian
Published 2019-06-01

Checkpoint inhibitors in ovarian cancer: A review of preclinical data

by David W. Doo, Lyse A. Norian, Rebecca C. Arend
Published 2019-08-01

Obesity triggers enhanced MDSC accumulation in murine renal tumors via elevated local production of CCL2.

by Malika Hale, Farah Itani, Claire M Buchta, Gal Wald, Megan Bing, Lyse A Norian
Published 2015-01-01

A Review of the Role of Wnt in Cancer Immunomodulation

by Whitney N. Goldsberry, Angelina Londoño, Troy D. Randall, Lyse A. Norian, Rebecca C. Arend
Published 2019-06-01

Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing...

by William J. Turbitt, Shannon K. Boi, Justin T. Gibson, Rachael M. Orlandella, Lyse A. Norian
Published 2021-05-01

Synergistic Induction of Apoptosis in Primary B-CLL Cells after Treatment with Recombinant Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand and Histone Deacetylase Inhibitor...

by Lyse A. Norian, Tamara A. Kucaba, James K. Earel, Tina Knutson, Rebecca L. vanOosten, Thomas S. Griffith
Published 2009-01-01

The Antidiabetic Agent Acarbose Improves Anti-PD-1 and Rapamycin Efficacy in Preclinical Renal Cancer

by Rachael M. Orlandella, William J. Turbitt, Justin T. Gibson, Shannon K. Boi, Peng Li, Daniel L. Smith, Lyse A. Norian
Published 2020-10-01

An antibiotic-responsive mouse model of fulminant ulcerative colitis.

by Silvia S Kang, Seth M Bloom, Lyse A Norian, Michael J Geske, Richard A Flavell, Thaddeus S Stappenbeck, Paul M Allen
Published 2008-03-01

Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy.

by Lyse A Norian, Timothy P Kresowik, Henry M Rosevear, Britnie R James, Timothy R Rosean, Andrew J Lightfoot, Tamara A Kucaba, Christopher Schwarz, Christine J Weydert, Michael D Henry, Thomas S Griffith
Published 2012-01-01

Inhibiting WNT Ligand Production for Improved Immune Recognition in the Ovarian Tumor Microenvironment

by Whitney N. Goldsberry, Selene Meza-Perez, Angelina I. Londoño, Ashwini A. Katre, Bryan T. Mott, Brandon M. Roane, Nidhi Goel, Jaclyn A. Wall, Sara J. Cooper, Lyse A. Norian, Troy D. Randall, Michael J. Birrer, Rebecca C. Arend
Published 2020-03-01

Obesity induces limited changes to systemic and local immune profiles in treatment-naive human clear cell renal cell carcinoma.

by Justin T Gibson, Katlyn E Norris, Gal Wald, Claire M Buchta Rosean, Lewis J Thomas, Shannon K Boi, Laura A Bertrand, Megan Bing, Jennifer B Gordetsky, Jessy Deshane, Peng Li, James A Brown, Kenneth G Nepple, Lyse A Norian
Published 2020-01-01

Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer

by David W. Doo, Selene Meza-Perez, Angelina I. Londoño, Whitney N. Goldsberry, Ashwini A. Katre, Jonathan D. Boone, Dylana J. Moore, Cindy T. Hudson, Ilaria Betella, Tyler R. McCaw, Abhishek Gangrade, Riyue Bao, Jason J. Luke, Eddy S. Yang, Michael J. Birrer, Dmytro Starenki, Sara J. Cooper, Donald J. Buchsbaum, Lyse A. Norian, Troy D. Randall, Rebecca C. Arend
Published 2020-04-01

Obesity diminishes response to PD-1-based immunotherapies in renal cancer

by Peng Li, Amani Makkouk, Jennifer Gordetsky, Eddy Yang, Lewis Thomas, Lakshminarayanan Nandagopal, Hesham Yasin, Rohan Garje, Shannon K Boi, Rachael M Orlandella, Justin Tyler Gibson, William James Turbitt, Gal Wald, Claire Buchta Rosean, Katlyn E Norris, Megan Bing, Laura Bertrand, Brett P Gross, Dmytro Starenki, Kristine I Farag, Robert E Sorge, James A Brown, David M Lubaroff, Rebecca C Arend, Kenneth Nepple, Tatiana T Marquez-Lago, Lyse A Norian
Published 2020-07-01