PD-L1 Multiplex and Quantitative Image Analysis for Molecular Diagnostics

by Fatima Abdullahi Sidi, Victoria Bingham, Stephanie G. Craig, Stephen McQuaid, Jacqueline James, Matthew P. Humphries, Manuel Salto-Tellez
Published 2021-12-01

Improving the Diagnostic Accuracy of the PD-L1 Test with Image Analysis and Multiplex Hybridization

by Matthew P. Humphries, Victoria Bingham, Fatima Abdullahi Sidi, Stephanie G. Craig, Stephen McQuaid, Jacqueline James, Manuel Salto-Tellez
Published 2020-04-01

Connectivity Mapping for Candidate Therapeutics Identification Using Next Generation Sequencing RNA-Seq Data.

by Darragh G McArt, Philip D Dunne, Jaine K Blayney, Manuel Salto-Tellez, Sandra Van Schaeybroeck, Peter W Hamilton, Shu-Dong Zhang
Published 2013-01-01

A Means of Assessing Deep Learning-Based Detection of ICOS Protein Expression in Colon Cancer

by Md Mostafa Kamal Sarker, Yasmine Makhlouf, Stephanie G. Craig, Matthew P. Humphries, Maurice Loughrey, Jacqueline A. James, Manuel Salto-Tellez, Paul O’Reilly, Perry Maxwell
Published 2021-07-01

Erratum to: JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer

by Yi Fang Lee, Lance David Miller, Xiu Bin Chan, Michael A. Black, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Edison T. Liu, Kartiki V. Desai
Published 2017-03-01

Establishing clonal cell lines with endothelial-like potential from CD9(hi), SSEA-1(-) cells in embryonic stem cell-derived embryoid bodies.

by Qizhou Lian, Keng Suan Yeo, Jianwen Que, Eileen Khia Way Tan, Fenggang Yu, Yijun Yin, Manuel Salto-Tellez, Reida Menshawe El Oakley, Sai-Kiang Lim
Published 2006-01-01

Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis.

by Clare M McCourt, Darragh G McArt, Ken Mills, Mark A Catherwood, Perry Maxwell, David J Waugh, Peter Hamilton, Joe M O'Sullivan, Manuel Salto-Tellez
Published 2013-01-01

Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

by Ross J Porter, Graeme I Murray, Abdo Alnabulsi, Matthew P Humphries, Jacqueline A James, Manuel Salto‐Tellez, Stephanie G Craig, Ji M Wang, Teizo Yoshimura, Mairi H McLean
Published 2021-09-01

The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation

by Matthew P. Humphries, Stephanie G. Craig, Rafal Kacprzyk, Natalie C. Fisher, Victoria Bingham, Stephen McQuaid, Graeme I. Murray, Damian McManus, Richard C. Turkington, Jacqueline James, Manuel Salto-Tellez
Published 2020-06-01

Systematic evaluation of PAXgene® tissue fixation for the histopathological and molecular study of lung cancer

by Mark Southwood, Tomasz Krenz, Natasha Cant, Manisha Maurya, Jana Gazdova, Perry Maxwell, Claire McGready, Ellen Moseley, Susan Hughes, Peter Stewart, Manuel Salto‐Tellez, Daniel Groelz, Doris Rassl, On behalf of the STRATfix Consortium
Published 2020-01-01

HistoClean: Open-source software for histological image pre-processing and augmentation to improve development of robust convolutional neural networks

by Kris D. McCombe, Stephanie G. Craig, Amélie Viratham Pulsawatdi, Javier I. Quezada-Marín, Matthew Hagan, Simon Rajendran, Matthew P. Humphries, Victoria Bingham, Manuel Salto-Tellez, Richard Gault, Jacqueline A. James
Published 2021-01-01

A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment

by Amélie Viratham Pulsawatdi, Stephanie G. Craig, Victoria Bingham, Kris McCombe, Matthew P. Humphries, Seedevi Senevirathne, Susan D. Richman, Phil Quirke, Leticia Campo, Enric Domingo, Timothy S. Maughan, Jacqueline A. James, Manuel Salto‐Tellez
Published 2020-10-01

Training and accreditation standards for pathologists undertaking clinical trial work

by Gabrielle Rees, Manuel Salto‐Tellez, Jessica L Lee, Karin Oien, Clare Verrill, Alex Freeman, Ilaria Mirabile, Nicholas P West, on behalf of the National Cancer Research Institute (NCRI) Cellular‐Molecular Pathology (CM‐Path) clinical trials working group
Published 2019-04-01

Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade.

by Jingli Zhuo, Ee Hong Tan, Benedict Yan, Lalchhandami Tochhawng, Manikandan Jayapal, Shiuan Koh, Hwee Kee Tay, Sutherland K Maciver, Shing Chuan Hooi, Manuel Salto-Tellez, Alan Prem Kumar, Yaw Chong Goh, Yaw Chyn Lim, Celestial T Yap
Published 2012-01-01

The clinical and molecular significance associated with STING signaling in breast cancer

by Eileen E. Parkes, Matthew P. Humphries, Elaine Gilmore, Fatima A. Sidi, Victoria Bingham, Su M. Phyu, Stephanie Craig, Catherine Graham, Joseph Miller, Daryl Griffin, Manuel Salto-Tellez, Stephen F. Madden, Richard D. Kennedy, Samuel F. Bakhoum, Stephen McQuaid, Niamh E. Buckley
Published 2021-06-01

Automated Tumour Recognition and Digital Pathology Scoring Unravels New Role for PD-L1 in Predicting Good Outcome in ER-/HER2+ Breast Cancer

by Matthew P. Humphries, Sean Hynes, Victoria Bingham, Delphine Cougot, Jacqueline James, Farah Patel-Socha, Eileen E. Parkes, Jaine K. Blayney, Michael A. O’Rorke, Gareth W. Irwin, Darragh G. McArt, Richard D. Kennedy, Paul B. Mullan, Stephen McQuaid, Manuel Salto-Tellez, Niamh E. Buckley
Published 2018-01-01