Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios

by Marc J Williams, Luis Zapata, Benjamin Werner, Chris P Barnes, Andrea Sottoriva, Trevor A Graham
Published 2020-03-01

Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data.

by Ketevan Chkhaidze, Timon Heide, Benjamin Werner, Marc J Williams, Weini Huang, Giulio Caravagna, Trevor A Graham, Andrea Sottoriva
Published 2019-07-01

Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

by Inês Sequeira, Mamunur Rashid, Inês M. Tomás, Marc J. Williams, Trevor A. Graham, David J. Adams, Alessandra Vigilante, Fiona M. Watt
Published 2020-11-01

Measuring single cell divisions in human tissues from multi-region sequencing data

by Benjamin Werner, Jack Case, Marc J. Williams, Ketevan Chkhaidze, Daniel Temko, Javier Fernández-Mateos, George D. Cresswell, Daniel Nichol, William Cross, Inmaculada Spiteri, Weini Huang, Ian P. M. Tomlinson, Chris P. Barnes, Trevor A. Graham, Andrea Sottoriva
Published 2020-02-01