What Drives Innovation: The Canadian Touch on Liposomal Therapeutics

by Ada W.Y. Leung, Carolyn Amador, Lin Chuan Wang, Urmi V. Mody, Marcel B. Bally
Published 2019-03-01

Combined RNAi-mediated suppression of Rictor and EGFR resulted in complete tumor regression in an orthotopic glioblastoma tumor model.

by Maite Verreault, Sherry A Weppler, Amelia Stegeman, Corinna Warburton, Dita Strutt, Dana Masin, Marcel B Bally
Published 2013-01-01

Nanoscale Reaction Vessels Designed for Synthesis of Copper-Drug Complexes Suitable for Preclinical Development.

by Mohamed Wehbe, Malathi Anantha, Ian Backstrom, Ada Leung, Kent Chen, Armaan Malhotra, Katarina Edwards, Marcel B Bally
Published 2016-01-01

Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response

by Roger Gilabert-Oriol, Gemma M. Ryan, Ada W.Y. Leung, Natalie S. Firmino, Kevin L. Bennewith, Marcel B. Bally
Published 2018-09-01

Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats

by Minghan Shi, Malathi Anantha, Mohamed Wehbe, Marcel B. Bally, David Fortin, Laurent-Olivier Roy, Gabriel Charest, Maxime Richer, Benoit Paquette, Léon Sanche
Published 2018-10-01

Treatment of colorectal cancer using a combination of liposomal irinotecan (Irinophore C™) and 5-fluorouracil.

by Jennifer I Hare, Robert W Neijzen, Malathi Anantha, Nancy Dos Santos, Natashia Harasym, Murray S Webb, Theresa M Allen, Marcel B Bally, Dawn N Waterhouse
Published 2013-01-01

Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell...

by Ada W Y Leung, Stacy S Hung, Ian Backstrom, Daniel Ricaurte, Brian Kwok, Steven Poon, Steven McKinney, Romulo Segovia, Jenna Rawji, Mohammed A Qadir, Samuel Aparicio, Peter C Stirling, Christian Steidl, Marcel B Bally
Published 2016-01-01

Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer.

by Wieslawa H Dragowska, Sherry A Weppler, Jun Chih Wang, Ling Yan Wong, Anita I Kapanen, Jenna S Rawji, Corinna Warburton, Mohammed A Qadir, Elizabeth Donohue, Michel Roberge, Sharon M Gorski, Karen A Gelmon, Marcel B Bally
Published 2013-01-01

Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo.

by Richard W Ahn, Susan L Barrett, Meera R Raja, Jennifer K Jozefik, Lidia Spaho, Haimei Chen, Marcel B Bally, Andrew P Mazar, Michael J Avram, Jane N Winter, Leo I Gordon, Lonnie D Shea, Thomas V O'Halloran, Teresa K Woodruff
Published 2013-01-01

Loss of Parkinson’s susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis

by Chandra Lebovitz, Nicole Wretham, Maryam Osooly, Katy Milne, Tia Dash, Shelby Thornton, Basile Tessier-Cloutier, Paalini Sathiyaseelan, Svetlana Bortnik, Nancy Erro Go, Elizabeth Halvorsen, Rachel A. Cederberg, Norman Chow, Nancy Dos Santos, Kevin L. Bennewith, Brad H. Nelson, Marcel B. Bally, Wan L. Lam, Sharon M. Gorski
Published 2021-01-01

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

by Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J. O’Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia, Farhia Kabeer, Daniel Lai, Priscilla Soriano, Judit Banáth, Derek S. Chiu, Damian Yap, Daniel D. Le, Frank B. Ye, Anni Zhang, Kelsie Thu, John Soong, Shu-chuan Lin, Angela Hsin Chin Tsai, Tomo Osako, Teresa Algara, Darren N. Saunders, Jason Wong, Jian Xian, Marcel B. Bally, James D. Brenton, Grant W. Brown, Sohrab P. Shah, David Cescon, Tak W. Mak, Carlos Caldas, Peter C. Stirling, Phil Hieter, Shankar Balasubramanian, Samuel Aparicio
Published 2017-02-01