Three-Dimensional Interactions Analysis of the Anticancer Target c-Src Kinase with Its Inhibitors

by Vibhu Jha, Marco Macchia, Tiziano Tuccinardi, Giulio Poli
Published 2020-08-01

Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis

by Francesca Gado, Maria Digiacomo, Marco Macchia, Simone Bertini, Clementina Manera
Published 2018-08-01

Extensive Reliability Evaluation of Docking-Based Target-Fishing Strategies

by Margherita Lapillo, Tiziano Tuccinardi, Adriano Martinelli, Marco Macchia, Antonio Giordano, Giulio Poli
Published 2019-02-01

miRNA Modulation and Antitumor Activity by the Extra-Virgin Olive Oil Polyphenol Oleacein in Human Melanoma Cells

by Sara Carpi, Sara Carpi, Beatrice Polini, Clementina Manera, Clementina Manera, Maria Digiacomo, Maria Digiacomo, Jasmine Esposito Salsano, Marco Macchia, Marco Macchia, Egeria Scoditti, Paola Nieri, Paola Nieri
Published 2020-09-01

Hydrogen Sulfide: A Worthwhile Tool in the Design of New Multitarget Drugs

by Simona Sestito, Giulia Nesi, Rongbiao Pi, Rongbiao Pi, Rongbiao Pi, Marco Macchia, Simona Rapposelli
Published 2017-09-01

Development and Validation of a Docking-Based Virtual Screening Platform for the Identification of New Lactate Dehydrogenase Inhibitors

by Carlotta Granchi, Alice Capecchi, Gianluca Del Frate, Adriano Martinelli, Marco Macchia, Filippo Minutolo, Tiziano Tuccinardi
Published 2015-05-01

Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors

by Carlotta Granchi, Isabella Caligiuri, Eleonora Bertelli, Giulio Poli, Flavio Rizzolio, Marco Macchia, Adriano Martinelli, Filippo Minutolo, Tiziano Tuccinardi
Published 2017-01-01

Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study

by Vibhu Jha, Marzia Biagi, Valeria Spinelli, Miriana Di Stefano, Marco Macchia, Filippo Minutolo, Carlotta Granchi, Giulio Poli, Tiziano Tuccinardi
Published 2021-12-01

Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma

by Silvia Tampucci, Sara Carpi, Maria Digiacomo, Beatrice Polini, Stefano Fogli, Susi Burgalassi, Marco Macchia, Paola Nieri, Clementina Manera, Daniela Monti
Published 2019-05-01

Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors

by Giulio Poli, Margherita Lapillo, Vibhu Jha, Nayla Mouawad, Isabella Caligiuri, Marco Macchia, Filippo Minutolo, Flavio Rizzolio, Tiziano Tuccinardi, Carlotta Granchi
Published 2019-01-01

Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors

by Simone Bertini, Giuseppe Saccomanni, Sara Del Carlo, Maria Digiacomo, Claudia Gargini, Ilaria Piano, Giuseppe Matteo Campisi, Riccardo Ghidoni, Marco Macchia, Clementina Manera
Published 2017-07-01

The Extra Virgin Olive Oil Polyphenol Oleocanthal Exerts Antifibrotic Effects in the Liver

by Daniela Gabbia, Sara Carpi, Sara Carpi, Samantha Sarcognato, Luana Cannella, Martina Colognesi, Michela Scaffidi, Beatrice Polini, Maria Digiacomo, Maria Digiacomo, Jasmine Esposito Salsano, Jasmine Esposito Salsano, Clementina Manera, Clementina Manera, Marco Macchia, Marco Macchia, Paola Nieri, Paola Nieri, Maria Carrara, Francesco Paolo Russo, Maria Guido, Sara De Martin
Published 2021-10-01

Effects on immune cells of a new 1,8-naphthyridin-2-one derivative and its analogues as selective CB2 agonists: implications in multiple sclerosis.

by Anna Maria Malfitano, Chiara Laezza, Alba D'Alessandro, Claudio Procaccini, Giuseppe Saccomanni, Tiziano Tuccinardi, Clementina Manera, Marco Macchia, Giuseppe Matarese, Patrizia Gazzerro, Maurizio Bifulco
Published 2013-01-01

Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands

by Filippo Minutolo, Simone Bertini, Adriano Martinelli, Gabriella Ortore, Giorgio Placanica, Giovanni Prota, Simona Rapposelli, Tiziano Tuccinardi, Shubin Sheng, Kathryn E. Carlson, Benita S. Katzenellenbogen, John A. Katzenellenbogen, Marco Macchia
Published 2006-06-01

A Proteomic Approach to Uncover Neuroprotective Mechanisms of Oleocanthal against Oxidative Stress

by Laura Giusti, Cristina Angeloni, Maria Cristina Barbalace, Serena Lacerenza, Federica Ciregia, Maurizio Ronci, Andrea Urbani, Clementina Manera, Maria Digiacomo, Marco Macchia, Maria Rosa Mazzoni, Antonio Lucacchini, Silvana Hrelia
Published 2018-08-01

Antioxidant and Neuroprotective Activity of Extra Virgin Olive Oil Extracts Obtained from Quercetano Cultivar Trees Grown in Different Areas of the Tuscany Region (Italy)

by Maria Cristina Barbalace, Lorenzo Zallocco, Daniela Beghelli, Maurizio Ronci, Serena Scortichini, Maria Digiacomo, Marco Macchia, Maria Rosa Mazzoni, Dennis Fiorini, Antonio Lucacchini, Silvana Hrelia, Laura Giusti, Cristina Angeloni
Published 2021-03-01

Immunomodulatory Activity of Electrospun Polyhydroxyalkanoate Fiber Scaffolds Incorporating Olive Leaf Extract

by Jose Gustavo De la Ossa, Alessandra Fusco, Bahareh Azimi, Jasmine Esposito Salsano, Maria Digiacomo, Maria-Beatrice Coltelli, Karen De Clerck, Ipsita Roy, Marco Macchia, Andrea Lazzeri, Giovanna Donnarumma, Serena Danti, Rossella Di Stefano
Published 2021-04-01

The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation

by Sara Carpi, Egeria Scoditti, Marika Massaro, Beatrice Polini, Clementina Manera, Maria Digiacomo, Jasmine Esposito Salsano, Giulio Poli, Tiziano Tuccinardi, Stefano Doccini, Filippo Maria Santorelli, Maria Annunziata Carluccio, Marco Macchia, Martin Wabitsch, Raffaele De Caterina, Paola Nieri
Published 2019-11-01