Phenotyping drug polypharmacology via eicosanoid profiling of blood[S]

by Jiao Song, Xuejun Liu, Tadimeti S. Rao, Leon Chang, Michael J. Meehan, Jonathan M. Blevitt, Jiejun Wu, Pieter C. Dorrestein, Marcos E. Milla
Published 2015-08-01

Isoproterenol acts as a biased agonist of the alpha-1A-adrenoceptor that selectively activates the MAPK/ERK pathway.

by Alicja J Copik, Aleksander Baldys, Khanh Nguyen, Sunil Sahdeo, Hoangdung Ho, Alan Kosaka, Paul J Dietrich, Bill Fitch, John R Raymond, Anthony P D W Ford, Donald Button, Marcos E Milla
Published 2015-01-01

An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism

by Jerod L. Ptacin, Carolina E. Caffaro, Lina Ma, Kristine M. San Jose Gall, Hans R. Aerni, Nicole V. Acuff, Rob W. Herman, Yelena Pavlova, Michael J. Pena, David B. Chen, Lilia K. Koriazova, Laura K. Shawver, Ingrid B. Joseph, Marcos E. Milla
Published 2021-08-01