A Decade of FGF Receptor Research in Bladder Cancer: Past, Present, and Future Challenges

by Erica di Martino, Darren C. Tomlinson, Margaret A. Knowles
Published 2012-01-01

ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer

by Erica di Martino, Olivia Alder, Carolyn D. Hurst, Margaret A. Knowles
Published 2019-04-01

FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms.

by Darren C Tomlinson, Euan W Baxter, Paul M Loadman, Mark A Hull, Margaret A Knowles
Published 2012-01-01

Identification of mutations in distinct regions of p85 alpha in urothelial cancer.

by Rebecca L Ross, Julie E Burns, Claire F Taylor, Paul Mellor, Deborah H Anderson, Margaret A Knowles
Published 2013-01-01

Towards a Next-Generation Sequencing Diagnostic Service for Tumour Genotyping: A Comparison of Panels and Platforms

by George J. Burghel, Carolyn D. Hurst, Christopher M. Watson, Phillip A. Chambers, Helen Dickinson, Paul Roberts, Margaret A. Knowles
Published 2015-01-01

Polycomb Repressor Complex 1 Member, BMI1 Contributes to Urothelial Tumorigenesis through p16-Independent Mechanisms

by Lia E. De Faveri, Carolyn D. Hurst, Jo-An Roulson, Henry Wood, Marta Sanchez-Carbayo, Margaret A. Knowles, Emma J. Chapman
Published 2015-10-01

Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes.

by Irene Lurkin, Robert Stoehr, Carolyn D Hurst, Angela A G van Tilborg, Margaret A Knowles, Arndt Hartmann, Ellen C Zwarthoff
Published 2010-01-01

Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation

by Paul Mellor, Jeremy D. S. Marshall, Xuan Ruan, Dielle E. Whitecross, Rebecca L. Ross, Margaret A. Knowles, Stanley A. Moore, Deborah H. Anderson
Published 2018-05-01

Use of Aleuria alantia Lectin Affinity Chromatography to Enrich Candidate Biomarkers from the Urine of Patients with Bladder Cancer

by Sarah R. Ambrose, Naheema S. Gordon, James C. Goldsmith, Wenbin Wei, Maurice P. Zeegers, Nicholas D. James, Margaret A. Knowles, Richard T. Bryan, Douglas G. Ward
Published 2015-09-01

The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study

by Tom D. Bunney, Shunzhou Wan, Nethaji Thiyagarajan, Ludovico Sutto, Sarah V. Williams, Paul Ashford, Hans Koss, Margaret A. Knowles, Francesco L. Gervasio, Peter V. Coveney, Matilda Katan
Published 2015-03-01

Mutations in SLC29A3, encoding an equilibrative nucleoside transporter ENT3, cause a familial histiocytosis syndrome (Faisalabad histiocytosis) and familial Rosai-Dorfman disease.

by Neil V Morgan, Mark R Morris, Hakan Cangul, Diane Gleeson, Anna Straatman-Iwanowska, Nicholas Davies, Stephen Keenan, Shanaz Pasha, Fatimah Rahman, Dean Gentle, Maaike P G Vreeswijk, Peter Devilee, Margaret A Knowles, Serdar Ceylaner, Richard C Trembath, Carlos Dalence, Erol Kismet, Vedat Köseoğlu, Hans-Christoph Rossbach, Paul Gissen, David Tannahill, Eamonn R Maher
Published 2010-02-01

TRPA1–FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p

by Jonathan Berrout, Eleni Kyriakopoulou, Lavanya Moparthi, Alexandra S. Hogea, Liza Berrout, Cristina Ivan, Mihaela Lorger, John Boyle, Chris Peers, Stephen Muench, Jacobo Elies Gomez, Xin Hu, Carolyn Hurst, Thomas Hall, Sujanitha Umamaheswaran, Laura Wesley, Mihai Gagea, Michael Shires, Iain Manfield, Margaret A. Knowles, Simon Davies, Klaus Suhling, Yurema Teijeiro Gonzalez, Neil Carragher, Kenneth Macleod, N. Joan Abbott, George A. Calin, Nikita Gamper, Peter M. Zygmunt, Zahra Timsah
Published 2017-10-01

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

by Sia Viborg Lindskrog, Frederik Prip, Philippe Lamy, Ann Taber, Clarice S. Groeneveld, Karin Birkenkamp-Demtröder, Jørgen Bjerggaard Jensen, Trine Strandgaard, Iver Nordentoft, Emil Christensen, Mateo Sokac, Nicolai J. Birkbak, Lasse Maretty, Gregers G. Hermann, Astrid C. Petersen, Veronika Weyerer, Marc-Oliver Grimm, Marcus Horstmann, Gottfrid Sjödahl, Mattias Höglund, Torben Steiniche, Karin Mogensen, Aurélien de Reyniès, Roman Nawroth, Brian Jordan, Xiaoqi Lin, Dejan Dragicevic, Douglas G. Ward, Anshita Goel, Carolyn D. Hurst, Jay D. Raman, Joshua I. Warrick, Ulrika Segersten, Danijel Sikic, Kim E. M. van Kessel, Tobias Maurer, Joshua J. Meeks, David J. DeGraff, Richard T. Bryan, Margaret A. Knowles, Tatjana Simic, Arndt Hartmann, Ellen C. Zwarthoff, Per-Uno Malmström, Núria Malats, Francisco X. Real, Lars Dyrskjøt
Published 2021-04-01