Challenges associated with biomarker‐based classification systems for Alzheimer's disease

by Ignacio Illán‐Gala, Jordi Pegueroles, Victor Montal, Eduard Vilaplana, María Carmona‐Iragui, Daniel Alcolea, Bradford C. Dickerson, Raquel Sánchez‐Valle, Mony J. deLeon, Rafael Blesa, Alberto Lleó, Juan Fortea, Alzheimer's Disease Neuroimaging Initiative
Published 2018-01-01

Diagnosis of prodromal and Alzheimer's disease dementia in adults with Down syndrome using neuropsychological tests

by Bessy Benejam, Laura Videla, Eduard Vilaplana, Isabel Barroeta, Maria Carmona‐Iragui, Miren Altuna, Silvia Valldeneu, Susana Fernandez, Sandra Giménez, Florencia Iulita, Diana Garzón, Alexandre Bejanin, David Bartrés‐Faz, Sebastià Videla, Daniel Alcolea, Rafael Blesa, Alberto Lleó, Juan Fortea
Published 2020-01-01

Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early‐onset Alzheimer's disease

by Alain D. Dekker, Yannick Vermeiren, Maria Carmona‐Iragui, Bessy Benejam, Laura Videla, Ellen Gelpi, Tony Aerts, Debby Van Dam, Susana Fernández, Alberto Lleó, Sebastian Videla, Anne Sieben, Jean‐Jacques Martin, Netherlands Brain Bank, Rafael Blesa, Juan Fortea, Peter P. De Deyn
Published 2018-01-01

Comparison of COVID-19 and Non-COVID-19 Pneumonia in Down Syndrome

by Diego Real de Asua, Miguel A. Mayer, María del Carmen Ortega, Jose M. Borrel, Teresa de Jesús Bermejo, Domingo González-Lamuño, Coral Manso, Fernando Moldenhauer, María Carmona-Iragui, Anke Hüls, Stephanie L. Sherman, Andre Strydom, Rafael de la Torre, Mara Dierssen
Published 2021-08-01

Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer’s disease-related inhibitory circuit dysfunction in adults with Down syndrome

by Olivia Belbin, Mei-Fang Xiao, Desheng Xu, Maria Carmona-Iragui, Jordi Pegueroles, Bessy Benejam, Laura Videla, Susana Fernández, Isabel Barroeta, Raúl Nuñez-Llaves, Victor Montal, Eduard Vilaplana, Miren Altuna, Jordi Clarimón, Daniel Alcolea, Rafael Blesa, Alberto Lleó, Paul F. Worley, Juan Fortea
Published 2020-08-01

VAMP-2 is a surrogate cerebrospinal fluid marker of Alzheimer-related cognitive impairment in adults with Down syndrome

by Alberto Lleó, Maria Carmona-Iragui, Laura Videla, Susana Fernández, Bessy Benejam, Jordi Pegueroles, Isabel Barroeta, Miren Altuna, Silvia Valldeneu, Mei-Fang Xiao, Desheng Xu, Raúl Núñez-Llaves, Marta Querol-Vilaseca, Sònia Sirisi, Alexandre Bejanin, M. Florencia Iulita, Jordi Clarimón, Rafael Blesa, Paul Worley, Daniel Alcolea, Juan Fortea, Olivia Belbin
Published 2021-06-01

Obesity impacts brain metabolism and structure independently of amyloid and tau pathology in healthy elderly

by Jordi Pegueroles, Adriana Pané, Eduard Vilaplana, Víctor Montal, Alexandre Bejanin, Laura Videla, María Carmona‐Iragui, Isabel Barroeta, Ainitze Ibarzabal, Anna Casajoana, Daniel Alcolea, Silvia Valldeneu, Miren Altuna, Ana deHollanda, Josep Vidal, Emilio Ortega, Ricardo Osorio, Antonio Convit, Rafael Blesa, Alberto Lleó, Juan Fortea, Amanda Jiménez, Alzheimer's Disease Neuroimaging Initiative
Published 2020-01-01

Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer’s disease in adults with Down syndrome

by Alberto Lleó, Henrik Zetterberg, Jordi Pegueroles, Thomas K. Karikari, María Carmona-Iragui, Nicholas J. Ashton, Victor Montal, Isabel Barroeta, Juan Lantero-Rodríguez, Laura Videla, Miren Altuna, Bessy Benejam, Susana Fernandez, Silvia Valldeneu, Diana Garzón, Alexandre Bejanin, Maria Florencia Iulita, Valle Camacho, Santiago Medrano-Martorell, Olivia Belbin, Jordi Clarimon, Sylvain Lehmann, Daniel Alcolea, Rafael Blesa, Kaj Blennow, Juan Fortea
Published 2021-07-01

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

by Rani K. Powers, Rachel Culp-Hill, Michael P. Ludwig, Keith P. Smith, Katherine A. Waugh, Ross Minter, Kathryn D. Tuttle, Hannah C. Lewis, Angela L. Rachubinski, Ross E. Granrath, María Carmona-Iragui, Rebecca B. Wilkerson, Darcy E. Kahn, Molishree Joshi, Alberto Lleó, Rafael Blesa, Juan Fortea, Angelo D’Alessandro, James C. Costello, Kelly D. Sullivan, Joaquin M. Espinosa
Published 2019-10-01

Medical vulnerability of individuals with Down syndrome to severe COVID-19–data from the Trisomy 21 Research Society and the UK ISARIC4C survey

by Anke Hüls, Alberto C.S. Costa, Mara Dierssen, R. Asaad Baksh, Stefania Bargagna, Nicole T. Baumer, Ana Claudia Brandão, Angelo Carfi, Maria Carmona-Iragui, Brian Allen Chicoine, Sujay Ghosh, Monica Lakhanpaul, Coral Manso, Miguel-Angel Mayer, Maria del Carmen Ortega, Diego Real de Asua, Anne-Sophie Rebillat, Lauren Ashley Russell, Giuseppina Sgandurra, Diletta Valentini, Stephanie L. Sherman, Andre Strydom
Published 2021-03-01