BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination

by Weiran Feng, Maria Jasin
Published 2017-09-01

Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination.

by Yufuko Akamatsu, Maria Jasin
Published 2010-10-01

Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.

by Michelle L Churchman, Ignasi Roig, Maria Jasin, Scott Keeney, Charles J Sherr
Published 2011-07-01

PARP Inhibitors in Clinical Use Induce Genomic Instability in Normal Human Cells.

by Shuhei Ito, Conleth G Murphy, Ekaterina Doubrovina, Maria Jasin, Mary Ellen Moynahan
Published 2016-01-01

The ATM signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes.

by Sarai Pacheco, Marina Marcet-Ortega, Julian Lange, Maria Jasin, Scott Keeney, Ignasi Roig
Published 2015-03-01

Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation

by Elizabeth M. Kass, Pei Xin Lim, Hildur R. Helgadottir, Mary Ellen Moynahan, Maria Jasin
Published 2016-10-01

Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination

by Carla M. Abreu, Rohit Prakash, Peter J. Romanienko, Ignasi Roig, Scott Keeney, Maria Jasin
Published 2018-10-01

Mouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosis.

by Ignasi Roig, James A Dowdle, Attila Toth, Dirk G de Rooij, Maria Jasin, Scott Keeney
Published 2010-08-01

ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes.

by Marco Barchi, Ignasi Roig, Monica Di Giacomo, Dirk G de Rooij, Scott Keeney, Maria Jasin
Published 2008-05-01

Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.

by Nicolas Siaud, Maria A Barbera, Akinori Egashira, Isabel Lam, Nicole Christ, Katharina Schlacher, Bing Xia, Maria Jasin
Published 2011-12-01

Homologous Recombination DNA Repair Genes Play a Critical Role in Reprogramming to a Pluripotent State

by Federico González, Daniela Georgieva, Fabio Vanoli, Zhong-Dong Shi, Matthias Stadtfeld, Thomas Ludwig, Maria Jasin, Danwei Huangfu
Published 2013-03-01

p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes.

by Marina Marcet-Ortega, Sarai Pacheco, Ana Martínez-Marchal, Helena Castillo, Elsa Flores, Maria Jasin, Scott Keeney, Ignasi Roig
Published 2017-06-01

Testicular Germ Cell Tumors Acquire Cisplatin Resistance by Rebalancing the Usage of DNA Repair Pathways

by Cinzia Caggiano, Francesca Cavallo, Teresa Giannattasio, Gioia Cappelletti, Pellegrino Rossi, Paola Grimaldi, Darren R. Feldman, Maria Jasin, Marco Barchi
Published 2021-02-01

Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis.

by James A Dowdle, Monika Mehta, Elizabeth M Kass, Bao Q Vuong, Akiko Inagaki, Dieter Egli, Maria Jasin, Scott Keeney
Published 2013-11-01

Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis.

by Mengcheng Luo, Jian Zhou, N Adrian Leu, Carla M Abreu, Jianle Wang, Montserrat C Anguera, Dirk G de Rooij, Maria Jasin, P Jeremy Wang
Published 2015-01-01

Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhi...

by Francesca Cavallo, Grazia Graziani, Cristina Antinozzi, Darren R Feldman, Jane Houldsworth, George J Bosl, Raju S K Chaganti, Mary Ellen Moynahan, Maria Jasin, Marco Barchi
Published 2012-01-01

RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines

by Phoebe S. Lee, Jun Fang, Lea Jessop, Timothy Myers, Preethi Raj, Nan Hu, Chaoyu Wang, Philip R. Taylor, Jianjun Wang, Javed Khan, Maria Jasin, Stephen J. Chanock
Published 2014-10-01

Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines

by Phoebe S. Lee, Jun Fang, Lea Jessop, Timothy Myers, Preethi Raj, Nan Hu, Chaoyu Wang, Philip R. Taylor, Jianjun Wang, Javed Khan, Maria Jasin, Stephen J. Chanock
Published 2014-01-01

Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer

by Felix Meyer, Saskia Becker, Sandra Classen, Ann Christin Parplys, Wael Yassin Mansour, Britta Riepen, Sara Timm, Claudia Ruebe, Maria Jasin, Harriet Wikman, Cordula Petersen, Kai Rothkamm, Kerstin Borgmann
Published 2020-01-01

Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase.

by Lukasz Wojtasz, Katrin Daniel, Ignasi Roig, Ewelina Bolcun-Filas, Huiling Xu, Verawan Boonsanay, Christian R Eckmann, Howard J Cooke, Maria Jasin, Scott Keeney, Michael J McKay, Attila Toth
Published 2009-10-01