Alphavirus replicon DNA expressing HIV antigens is an excellent prime for boosting with recombinant modified vaccinia Ankara (MVA) or with HIV gp140 protein antigen.

by Maria L Knudsen, Karl Ljungberg, Roger Tatoud, Jonathan Weber, Mariano Esteban, Peter Liljeström
Published 2015-01-01

Potent therapeutic efficacy of an alphavirus replicon DNA vaccine expressing human papilloma virus E6 and E7 antigens

by Stephanie van de Wall, Karl Ljungberg, Peng Peng Ip, Annemarie Boerma, Maria L. Knudsen, Hans W. Nijman, Peter Liljeström, Toos Daemen
Published 2018-10-01

The adjuvant activity of alphavirus replicons is enhanced by incorporating the microbial molecule flagellin into the replicon.

by Maria L Knudsen, Daniel X Johansson, Linda Kostic, Eva K L Nordström, Karin Tegerstedt, Anna Pasetto, Steven E Applequist, Karl Ljungberg, Jean-Claude Sirard, Peter Liljeström
Published 2013-01-01