The effects of exendin-4 treatment on graft failure: an animal study using a novel re-vascularized minimal human islet transplant model.

by Afaf Sahraoui, Maria Sörhede Winzell, Tracy Gorman, Dave M Smith, Stanko Skrtic, Merete Hoeyem, Shadab Abadpour, Lars Johansson, Olle Korsgren, Aksel Foss, Hanne Scholz
Published 2015-01-01

The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1.

by Linda Sundström, Susanna Myhre, Monika Sundqvist, Andrea Ahnmark, William McCoull, Piotr Raubo, Sam D Groombridge, Magnus Polla, Ann-Christin Nyström, Lisbeth Kristensson, Mats Någård, Maria Sörhede Winzell
Published 2017-01-01

The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass

by Mahabuba Jahan, Peter Johnström, Ram K. Selvaraju, Marie Svedberg, Maria Sörhede Winzell, Jenny Bernström, Lee Kingston, Magnus Schou, Zhisheng Jia, Stanko Skrtic, Lars Johansson, Olle Korsgren, Lars Farde, Christer Halldin, Olof Eriksson
Published 2018-12-01

Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction.

by Sara F Hansson, Alex-Xianghua Zhou, Paulina Vachet, Jan W Eriksson, Maria J Pereira, Stanko Skrtic, Helen Jongsma Wallin, Anders Ericsson-Dahlstrand, Daniel Karlsson, Andrea Ahnmark, Maria Sörhede Winzell, Maria Chiara Magnone, Pia Davidsson
Published 2018-01-01

Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients.

by Stanko Skrtic, Björn Tyrberg, Malin Broberg, Hans Ericsson, Volker Schnecke, Magnus Kjaer, Marcus Hompesch, Eva-Marie Andersson, Erik Ryberg, Alexander Aivazidis, Charlotte Wennberg Huldt, Lars Löfgren, Linda Morrow, Joanna Parkinson, Tina Rydén-Bergsten, Elaine Watkins, Maria Sörhede Winzell
Published 2018-01-01

A method for the generation of human stem cell-derived alpha cells

by Quinn P. Peterson, Adrian Veres, Lihua Chen, Michael Q. Slama, Jennifer H. R. Kenty, Shaimaa Hassoun, Matthew R. Brown, Haiqiang Dou, Caden D. Duffy, Quan Zhou, Aleksey V. Matveyenko, Björn Tyrberg, Maria Sörhede-Winzell, Patrik Rorsman, Douglas A. Melton
Published 2020-05-01