700 EphA2/CD137 Bicycle tumor-targeted immune cell agonists (TICAsTM) induce tumor regressions, immunogenic memory, and reprogramming of the tumor immune microenvironment

by Jun Ma, Sailaja Battula, Kristen Hurov, Johanna lahdenranta, Gemma Mudd, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Marianna Kleyman, Jessica Kublin, Liuhong Chen, Eric Haines, Kevin McDonnell, Philip Brandish, Nicholas Keen
Published 2020-11-01

MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme

by Yingzhong Li, Nikola A. Ivica, Ting Dong, Dimitrios P. Papageorgiou, Yanpu He, Douglas R. Brown, Marianna Kleyman, Guangan Hu, Walter W. Chen, Lucas B. Sullivan, Amanda Del Rosario, Paula T. Hammond, Matthew G. Vander Heiden, Jianzhu Chen
Published 2020-09-01

Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist

by Sailaja Battula, Kristen Hurov, Johanna lahdenranta, Gemma Mudd, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Marianna Kleyman, Jessica Kublin, Liuhong Chen, Eric Haines, Kevin McDonnell, Philip Brandish, Nicholas Keen, Rachel Dods, Rachid Lani, Katerine Van Rietschoten, Tom Stephen, Fanglei You
Published 2021-01-01