An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations

by Akash Pandya, Mark J. Howard, Mire Zloh, Paul A. Dalby
Published 2018-09-01

¹H NMR spectroscopy profiling of metabolic reprogramming of Chinese hamster ovary cells upon a temperature shift during culture.

by Jane L Wagstaff, Rosalyn J Masterton, Jane F Povey, C Mark Smales, Mark J Howard
Published 2013-01-01

NMR metabolomics reveals effects of Cryptosporidium infections on host cell metabolome

by Christopher N. Miller, Charalampos G. Panagos, William R. T. Mosedale, Martin Kváč, Mark J. Howard, Anastasios D. Tsaousis
Published 2019-04-01

Structural guided scaffold phage display libraries as a source of bio-therapeutics.

by Y K Stella Man, Danielle DiCara, Nicole Chan, Sandrine Vessillier, Stephen J Mather, Michelle L Rowe, Mark J Howard, John F Marshall, Ahuva Nissim
Published 2013-01-01

Protein disulfide-isomerase interacts with a substrate protein at all stages along its folding pathway.

by Alistair G Irvine, A Katrine Wallis, Narinder Sanghera, Michelle L Rowe, Lloyd W Ruddock, Mark J Howard, Richard A Williamson, Claudia A Blindauer, Robert B Freedman
Published 2014-01-01

FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR)

by Andrew D. Lawrence, Samantha L. Taylor, Alan Scott, Michelle L. Rowe, Christopher M. Johnson, Stephen E. J. Rigby, Michael A. Geeves, Richard W. Pickersgill, Mark J. Howard, Martin J. Warren
Published 2014-07-01

Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of th...

by Emily Saintas, Liam Abrahams, Gulshan T Ahmad, Anu-Oluwa M Ajakaiye, Abdulaziz S H A M AlHumaidi, Candice Ashmore-Harris, Iain Clark, Usha K Dura, Carine N Fixmer, Chinedu Ike-Morris, Mireia Mato Prado, Danielle Mccullough, Shishir Mishra, Katia M U Schöler, Husne Timur, Maxwell D C Williamson, Markella Alatsatianos, Basma Bahsoun, Edith Blackburn, Catherine E Hogwood, Pamela E Lithgow, Michelle Rowe, Lyto Yiangou, Florian Rothweiler, Jindrich Cinatl, Richard Zehner, Anthony J Baines, Michelle D Garrett, Campbell W Gourlay, Darren K Griffin, William J Gullick, Emma Hargreaves, Mark J Howard, Daniel R Lloyd, Jeremy S Rossman, C Mark Smales, Anastasios D Tsaousis, Tobias von der Haar, Mark N Wass, Martin Michaelis
Published 2017-01-01