Augmentation therapy in alpha-1 antitrypsin deficiency: advances and controversies

by Adriano R. Tonelli, Mark L. Brantly
Published 2010-10-01

Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function.

by Aabida Saferali, Jee Lee, Don D Sin, Farshid N Rouhani, Mark L Brantly, Andrew J Sandford
Published 2014-01-01

Alpha-1 Antitrypsin Attenuates Acute Lung Allograft Injury in a Rat Lung Transplant Model

by Amir M. Emtiazjoo, MD, MSc, Hanbo Hu, MD, Li Lu, MD, PhD, Mark L. Brantly, MD
Published 2019-06-01

Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils

by Jungnam Lee, Yuanqing Lu, Regina Oshins, Jesse West, Craig G. Moneypenny, Kyudong Han, Kyudong Han, Mark L. Brantly
Published 2020-11-01

Cytosolic, autocrine alpha-1 proteinase inhibitor (A1PI) inhibits caspase-1 and blocks IL-1β dependent cytokine release in monocytes.

by Yonggang Wang, Yong He, Bindu Abraham, Farshid N Rouhani, Mark L Brantly, Dorothy E Scott, Jennifer L Reed
Published 2012-01-01

Bronchoalveolar lavage (BAL) cells in idiopathic pulmonary fibrosis express a complex pro-inflammatory, pro-repair, angiogenic activation pattern, likely associated with macrophage...

by Jungnam Lee, Ivan Arisi, Ermanno Puxeddu, Lazarus K Mramba, Massimo Amicosante, Carmen M Swaisgood, Marco Pallante, Mark L Brantly, C Magnus Sköld, Cesare Saltini
Published 2018-01-01

A checkpoint on innate myeloid cells in pulmonary arterial hypertension

by Andrew J. Bryant, Chunhua Fu, Yuanquing Lu, Mark L. Brantly, Borna Mehrad, Lyle L. Moldawer, Todd M. Brusko, Evan L. Brittain, James D. West, Eric D. Austin, Rizwan Hamid
Published 2019-01-01

In Situ Transplantation of Alginate Bioencapsulated Adipose Tissues Derived Stem Cells (ADSCs) via Hepatic Injection in a Mouse Model.

by Mong-Jen Chen, Yuanqing Lu, Nicholas E Simpson, Mark J Beveridge, Ahmed S Elshikha, Mohammad Ahsanul Akbar, Hsin-Yin Tsai, Stephanie Hinske, Junling Qin, Christian R Grunwitz, Tina Chen, Mark L Brantly, Sihong Song
Published 2015-01-01