Modulation of Myocardial Contraction by Peroxynitrite

by Mark eKohr, Steve eRoof, Jay eZweier, Mark T Ziolo
Published 2012-12-01

Myofilament calcium sensitivity: Role in regulation of in vivo cardiac contraction and relaxation

by Jae-Hoon Chung, Brandon J Biesiadecki, Mark T Ziolo, Jonathan P Davis, Paul M L Janssen
Published 2016-12-01

Staurosporine Inhibits Frequency-Dependent Myofilament Desensitization in Intact Rabbit Cardiac Trabeculae

by Kenneth D. Varian, Brandon J. Biesiadecki, Mark T. Ziolo, Jonathan P. Davis, Paul M. L. Janssen
Published 2012-01-01

CXL-1020, a Novel Nitroxyl (HNO) Prodrug, Is More Effective than Milrinone in Models of Diastolic Dysfunction—A Cardiovascular Therapeutic: An Efficacy and Safety Study in the Rat...

by Steve R. Roof, Yukie Ueyama, Reza Mazhari, Robert L. Hamlin, J. Craig Hartman, Mark T. Ziolo, John E. Reardon, Carlos L. del Rio
Published 2017-11-01

Myofilament Calcium Sensitivity: Mechanistic Insight into TnI Ser-23/24 and Ser-150 Phosphorylation Integration

by Hussam E Salhi, Hussam E Salhi, Nathan C Hassel, Nathan C Hassel, Jalal K Siddiqui, Jalal K Siddiqui, Elizabeth A Brundage, Elizabeth A Brundage, Mark T Ziolo, Mark T Ziolo, Paul M L Janssen, Paul M L Janssen, Jonathan P Davis, Jonathan P Davis, Brandon J Biesiadecki, Brandon J Biesiadecki
Published 2016-12-01

Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation.

by Jerry Curran, Lifei Tang, Steve R Roof, Sathya Velmurugan, Ashley Millard, Stephen Shonts, Honglan Wang, Demetrio Santiago, Usama Ahmad, Matthew Perryman, Donald M Bers, Peter J Mohler, Mark T Ziolo, Thomas R Shannon
Published 2014-01-01

Diesterified nitrone rescues nitroso-redox levels and increases myocyte contraction via increased SR Ca(2+) handling.

by Christopher J Traynham, Steve R Roof, Honglan Wang, Robert A Prosak, Lifei Tang, Serge Viatchenko-Karpinski, Hsiang-Ting Ho, Ira O Racoma, Dominic J Catalano, Xin Huang, Yongbin Han, Shang-U Kim, Sandor Gyorke, George E Billman, Frederick A Villamena, Mark T Ziolo
Published 2012-01-01

Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease

by Vikram Shettigar, Bo Zhang, Sean C. Little, Hussam E. Salhi, Brian J. Hansen, Ning Li, Jianchao Zhang, Steve R. Roof, Hsiang-Ting Ho, Lucia Brunello, Jessica K. Lerch, Noah Weisleder, Vadim V. Fedorov, Federica Accornero, Jill A. Rafael-Fortney, Sandor Gyorke, Paul M. L. Janssen, Brandon J. Biesiadecki, Mark T. Ziolo, Jonathan P. Davis
Published 2016-02-01

NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model

by Jennifer M. Peterson, David J. Wang, Vikram Shettigar, Steve R. Roof, Benjamin D. Canan, Nadine Bakkar, Jonathan Shintaku, Jin-Mo Gu, Sean C. Little, Nivedita M. Ratnam, Priya Londhe, Leina Lu, Christopher E. Gaw, Jennifer M. Petrosino, Sandya Liyanarachchi, Huating Wang, Paul M. L. Janssen, Jonathan P. Davis, Mark T. Ziolo, Sudarshana M. Sharma, Denis C. Guttridge
Published 2018-08-01