Tumor Restrictions to Oncolytic Virus

by Markus Vähä-Koskela, Ari Hinkkanen
Published 2014-04-01

Incomplete but infectious vaccinia virions are produced in the absence of oncolysis in feline SCCF1 cells.

by Suvi Parviainen, Karoliina Autio, Markus Vähä-Koskela, Kilian Guse, Sari Pesonen, Thomas J Rosol, Fang Zhao, Akseli Hemminki
Published 2015-01-01

Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

by Siri Tähtinen, Saija Kaikkonen, Maiju Merisalo-Soikkeli, Susanna Grönberg-Vähä-Koskela, Anna Kanerva, Suvi Parviainen, Markus Vähä-Koskela, Akseli Hemminki
Published 2015-01-01

MicroRNA-mediated suppression of oncolytic adenovirus replication in human liver.

by Erkko Ylösmäki, Sergio Lavilla-Alonso, Sari Jäämaa, Markus Vähä-Koskela, Taija af Hällström, Akseli Hemminki, Johanna Arola, Heikki Mäkisalo, Kalle Saksela
Published 2013-01-01

Safety and biodistribution of a double-deleted oncolytic vaccinia virus encoding CD40 ligand in laboratory Beagles

by Karoliina Autio, Anna Knuuttila, Anja Kipar, Sari Pesonen, Kilian Guse, Suvi Parviainen, Minna Rajamäki, Outi Laitinen-Vapaavuori, Markus Vähä-Koskela, Anna Kanerva, Akseli Hemminki
Published 2014-01-01

Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity

by Mari Hirvinen, Cristian Capasso, Kilian Guse, Mariangela Garofalo, Andrea Vitale, Marko Ahonen, Lukasz Kuryk, Markus Vähä-Koskela, Akseli Hemminki, Vittorio Fortino, Dario Greco, Vincenzo Cerullo
Published 2016-01-01

Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas

by Minna Niittykoski, Mikael von und zu Fraunberg, Miika Martikainen, Tuomas Rauramaa, Arto Immonen, Susanna Koponen, Ville Leinonen, Markus Vähä-Koskela, Qiwei Zhang, Florian Kühnel, Ya-Fang Mei, Seppo Ylä-Herttuala, Juha E. Jääskeläinen, Ari Hinkkanen
Published 2017-10-01

PROX1 is a transcriptional regulator of MMP14

by Silvia Gramolelli, Jianpin Cheng, Ines Martinez-Corral, Markus Vähä-Koskela, Endrit Elbasani, Elisa Kaivanto, Ville Rantanen, Krista Tuohinto, Sampsa Hautaniemi, Mark Bower, Caj Haglund, Kari Alitalo, Taija Mäkinen, Tatiana V. Petrova, Kaisa Lehti, Päivi M. Ojala
Published 2018-06-01

Overcoming tumor resistance by heterologous adeno-poxvirus combination therapy

by Markus Vähä-Koskela, Siri Tähtinen, Susanna Grönberg-Vähä-Koskela, Kristian Taipale, Dipongkor Saha, Maiju Merisalo-Soikkeli, Marko Ahonen, Noora Rouvinen-Lagerström, Mari Hirvinen, Ville Veckman, Sampsa Matikainen, Fang Zhao, Päivi Pakarinen, Jarmo Salo, Anna Kanerva, Vincenzo Cerullo, Akseli Hemminki
Published 2014-01-01

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

by Daria Bulanova, Aleksandr Ianevski, Andrii Bugai, Yevhen Akimov, Suvi Kuivanen, Henrik Paavilainen, Laura Kakkola, Jatin Nandania, Laura Turunen, Tiina Ohman, Hanna Ala-Hongisto, Hanna M. Pesonen, Marika S. Kuisma, Anni Honkimaa, Emma L. Walton, Valentyn Oksenych, Martina B. Lorey, Dmitry Guschin, Jungmin Shim, Jinhee Kim, Thoa T. Than, So Young Chang, Veijo Hukkanen, Evgeny Kulesskiy, Varpu S. Marjomaki, Ilkka Julkunen, Tuula A. Nyman, Sampsa Matikainen, Jani S. Saarela, Famara Sane, Didier Hober, Gülsah Gabriel, Jef K. De Brabander, Miika Martikainen, Marc P. Windisch, Ji-Young Min, Roberto Bruzzone, Tero Aittokallio, Markus Vähä-Koskela, Olli Vapalahti, Arto Pulk, Vidya Velagapudi, Denis E. Kainov
Published 2017-09-01