Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands.

by Anne N Shemon, Gary L Heil, Alexey E Granovsky, Mathew M Clark, Dan McElheny, Alexander Chimon, Marsha R Rosner, Shohei Koide
Published 2010-05-01

Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas.

by Olga Martinho, Sara Granja, Teresa Jaraquemada, Cláudia Caeiro, Vera Miranda-Gonçalves, Mrinalini Honavar, Paulo Costa, Margarida Damasceno, Marsha R Rosner, José M Lopes, Rui M Reis
Published 2012-01-01

Observation and Control of Gene Expression Noise: Barrier Crossing Analogies Between Drug Resistance and Metastasis

by Michael Tyler Guinn, Michael Tyler Guinn, Michael Tyler Guinn, Yiming Wan, Yiming Wan, Sarah Levovitz, Sarah Levovitz, Dongbo Yang, Marsha R. Rosner, Gábor Balázsi, Gábor Balázsi
Published 2020-10-01

RKIP inhibition in cervical cancer is associated with higher tumor aggressive behavior and resistance to cisplatin therapy.

by Olga Martinho, Filipe Pinto, Sara Granja, Vera Miranda-Gonçalves, Marise A R Moreira, Luis F J Ribeiro, Celso di Loreto, Marsha R Rosner, Adhemar Longatto-Filho, Rui Manuel Reis
Published 2013-01-01

Limited inhibition of multiple nodes in a driver network blocks metastasis

by Ali Ekrem Yesilkanal, Dongbo Yang, Andrea Valdespino, Payal Tiwari, Alan U Sabino, Long Chi Nguyen, Jiyoung Lee, Xiao-He Xie, Siqi Sun, Christopher Dann, Lydia Robinson-Mailman, Ethan Steinberg, Timothy Stuhlmiller, Casey Frankenberger, Elizabeth Goldsmith, Gary L Johnson, Alexandre F Ramos, Marsha R Rosner
Published 2021-05-01