Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2′-PO4 recognition and ADP-ribosylation

by Ankan Banerjee, Annum Munir, Leonora Abdullahu, Masad J. Damha, Yehuda Goldgur, Stewart Shuman
Published 2019-01-01

Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV Therapy

by Mayumi Takahashi, Haitang Li, Jiehua Zhou, Pritsana Chomchan, Veenu Aishwarya, Masad J. Damha, John J. Rossi
Published 2019-09-01

Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids

by Naira Souleimanian, Glen F Deleavey, Harris Soifer, Sijian Wang, Katrin Tiemann, Masad J Damha, Cy A Stein
Published 2012-01-01

Antibody-Antisense Oligonucleotide Conjugate Downregulates a Key Gene in Glioblastoma Stem Cells

by Amy E. Arnold, Elise Malek-Adamian, Phuong U. Le, Anika Meng, Saúl Martínez-Montero, Kevin Petrecca, Masad J. Damha, Molly S. Shoichet
Published 2018-06-01

Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells

by Elena Moroz, Soo Hyeon Lee, Ken Yamada, François Halloy, Saúl Martínez-Montero, Hartmut Jahns, Jonathan Hall, Masad J Damha, Bastien Castagner, Jean-Christophe Leroux
Published 2016-01-01

A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution

by Bishnu P Paudel, Aaron Lavel Moye, Hala Abou Assi, Roberto El-Khoury, Scott B Cohen, Jessica K Holien, Monica L Birrento, Siritron Samosorn, Kamthorn Intharapichai, Christopher G Tomlinson, Marie-Paule Teulade-Fichou, Carlos González, Jennifer L Beck, Masad J Damha, Antoine M van Oijen, Tracy M Bryan
Published 2020-07-01

Modified nucleic acids for the regulation of gene expression: an investigation of synthetic 2' and 4' fluorinated oligonucleotides

by Deleavey, Glen
Published 2014

Advancements in the synthesis of oligoribonucleotides on solid support and in solution: Ionic soluble supports, blockmer ribonucleotide amidites, and orthogonal linkers

by Hassler, Matthew
Published 2013

Chemistry for gene silencing: 4'-modified and 2'-fluorinated nucleosides and oligonucleotides

by Watts, Jonathan
Published 2008

Synthesis and gene silencing activity of ribonucleic acid duplexes containing 3'-deoxy-3'-thiothymidine

by Isaac, Siara
Published 2009

Synthesis of oxepane nucleosides by ring expansion and ring closing routes

by Gallant, Pascal
Published 2011

New methods for the synthesis of RNA, novel RNA pro-drugs and RNA microarrays

by Lackey, Jeremy
Published 2010

Modified nucleotides and nucleic acids for the discovery of antiretroviral agents targeting HIV-1 reverse transcriptase

by Wahba, Alexander
Published 2010

Photophysical properties of single and double stranded DNA containing 6-phenylpyrrolocytosine (PHPC)

by Azizi, Fereshteh
Published 2013