Optical Imaging of Tumor Hypoxia and Evaluation of Efficacy of a Hypoxia-Targeting Drug in Living Animals

by Hiroshi Harada, Shinae Kizaka-Kondoh, Masahiro Hiraoka
Published 2005-07-01

Microenvironment and Radiation Therapy

by Michio Yoshimura, Satoshi Itasaka, Hiroshi Harada, Masahiro Hiraoka
Published 2013-01-01

Outcome measures reported in abstracts of randomized controlled trials in leading clinical journals: A bibliometric study

by Takeshi Seta, Yoshimitsu Takahashi, Yukitaka Yamashita, Masahiro Hiraoka, Takeo Nakayama
Published 2020-07-01

Strategies To Assess Hypoxic/HIF-1-Active Cancer Cells for the Development of Innovative Radiation Therapy

by Masahiro Hiraoka, Hiroshi Harada, Yuxi Zhu, Lihua Zeng, Chan Joo Yeom
Published 2011-09-01

Microenvironments and Cellular Characteristics in the Micro Tumor Cords of Malignant Solid Tumors

by Hiroshi Harada, Yoko Goto, Masahiro Hiraoka, Yuxi Zhu, Chan Joo Yeom
Published 2012-10-01

In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system.

by Takahiro Kuchimaru, Tetsuya Kadonosono, Shotaro Tanaka, Takashi Ushiki, Masahiro Hiraoka, Shinae Kizaka-Kondoh
Published 2010-12-01

Correlation between urinary dose and delayed radiation cystitis after 78 Gy intensity-modulated radiotherapy for high-risk prostate cancer: A 10-year follow-up study of genitourina...

by Haruo Inokuchi, Takashi Mizowaki, Yoshiki Norihisa, Kenji Takayama, Itaru Ikeda, Kiyonao Nakamura, Masahiro Hiraoka
Published 2017-10-01

Optimization of a newly defined target volume in fiducial marker-based dynamic tumor-tracking radiotherapy

by Yusuke Iizuka, Yukinori Matsuo, Mitsuhiro Nakamura, Satoshi Kozawa, Nami Ueki, Takamasa Mitsuyoshi, Takashi Mizowaki, Masahiro Hiraoka
Published 2017-10-01

The impact of age on the risk of ipsilateral breast tumor recurrence after breast-conserving therapy in breast cancer patients with a > 5 mm margin treated without boost irradiatio...

by Yuka Ono, Michio Yoshimura, Kimiko Hirata, Chikako Yamauchi, Masakazu Toi, Eiji Suzuki, Masahiro Takada, Masahiro Hiraoka, Takashi Mizowaki
Published 2019-07-01

UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization

by Ryota Nakashima, Yoko Goto, Sho Koyasu, Minoru Kobayashi, Akiyo Morinibu, Michio Yoshimura, Masahiro Hiraoka, Ester M. Hammond, Hiroshi Harada
Published 2017-07-01

Protection of cardiomyocytes from the hypoxia-mediated injury by a peptide targeting the activator of G-protein signaling 8.

by Motohiko Sato, Masahiro Hiraoka, Hiroko Suzuki, Miho Sakima, Abdullah Al Mamun, Yukiko Yamane, Takayuki Fujita, Utako Yokoyama, Satoshi Okumura, Yoshihiro Ishikawa
Published 2014-01-01

In vivo imaging of brain ischemia using an oxygen-dependent degradative fusion protein probe.

by Youshi Fujita, Takahiro Kuchimaru, Tetsuya Kadonosono, Shotaro Tanaka, Yoshiki Hase, Hidekazu Tomimoto, Masahiro Hiraoka, Shinae Kizaka-Kondoh, Masafumi Ihara, Ryosuke Takahashi
Published 2012-01-01

Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks.

by Mari Fujita, Hiroyuki Sasanuma, Kimiyo N Yamamoto, Hiroshi Harada, Aya Kurosawa, Noritaka Adachi, Masato Omura, Masahiro Hiraoka, Shunichi Takeda, Kouji Hirota
Published 2013-01-01

Noninvasive tracking of donor cell homing by near-infrared fluorescence imaging shortly after bone marrow transplantation.

by Takashi Ushiki, Shinae Kizaka-Kondoh, Eishi Ashihara, Shotaro Tanaka, Masayoshi Masuko, Hideyo Hirai, Shinya Kimura, Yoshifusa Aizawa, Taira Maekawa, Masahiro Hiraoka
Published 2010-01-01

Hypofractionated intensity-modulated radiotherapy with concurrent chemotherapy for elderly patients with locally advanced pancreatic carcinoma

by Takahiro Iwai, Michio Yoshimura, Ryo Ashida, Yoko Goto, Takahiro Kishi, Satoshi Itasaka, Keiko Shibuya, Masashi Kanai, Toshihiko Masui, Akihisa Fukuda, Hiroyoshi Isoda, Masahiro Hiraoka, Takashi Mizowaki
Published 2020-11-01

Clinical evaluation of intensity-modulated radiotherapy for locally advanced pancreatic cancer

by Yoko Goto, Akira Nakamura, Ryo Ashida, Katsuyuki Sakanaka, Satoshi Itasaka, Keiko Shibuya, Shigemi Matsumoto, Masashi Kanai, Hiroyoshi Isoda, Toshihiko Masui, Yuzo Kodama, Kyoichi Takaori, Masahiro Hiraoka, Takashi Mizowaki
Published 2018-06-01

Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imaging.

by Tetsuya Kadonosono, Takahiro Kuchimaru, Shuichi Yamada, Yumi Takahashi, Atsushi Murakami, Taeko Tani, Hitomi Watanabe, Tomoharu Tanaka, Kiichi Hirota, Masahiro Inoue, Tetsuya Tsukamoto, Takeshi Toyoda, Koji Urano, Kazuhiko Machida, Tomoo Eto, Tomoyuki Ogura, Hideki Tsutsumi, Mamoru Ito, Masahiro Hiraoka, Gen Kondoh, Shinae Kizaka-Kondoh
Published 2011-01-01

ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair.

by Masataka Tsuda, Kosai Cho, Masato Ooka, Naoto Shimizu, Reiko Watanabe, Akira Yasui, Yuka Nakazawa, Tomoo Ogi, Hiroshi Harada, Keli Agama, Jun Nakamura, Ryuta Asada, Haruna Fujiike, Tetsushi Sakuma, Takashi Yamamoto, Junko Murai, Masahiro Hiraoka, Kaoru Koike, Yves Pommier, Shunichi Takeda, Kouji Hirota
Published 2017-01-01