Can We Build Artificial Stem Cell Compartments?

by Semino, Carlos E.
Published 2015

Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform

by Cosgrove, P. A., Dunn, R. T., Stolz, D. B., Hamadeh, H., Afshari, C., McBride, H., Long, Thomas J, Griffith, Linda G
Published 2018

Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System

by Kostrzewski, T., Stokes, C. L., Hughes, D. J., Tsamandouras, Nikolaos, Griffith, Linda G, Cirit, Murat
Published 2018

Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS)

by Stokes, Cynthia L., Maass, Christian Alexander, Griffith, Linda G, Cirit, Murat
Published 2018

Cytokine-associated drug toxicity in human hepatocytes is associated signaling network dysregulation

by Hendriks, Bart S., Cosgrove, Benjamin D., Alexopoulos, Leonidas G., Hang, Ta-Chun, Sorger, Peter K., Griffith, Linda G., Lauffenburger, Douglas A.
Published 2011

ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker

by Yoneyama, Toshie, Gorry, Michael, Sobo-Vujanovic, Andrea, Lin, Yan, Vujanovic, Lazar, Gaither-Davis, Autumn, Moss, Marcia L., Stabile, Laura P., Herman, James, Vujanovic, Nikola L., Miller, Miles Aaron, Griffith, Linda G, Lauffenburger, Douglas A
Published 2018

Modification of proteolytic activity matrix analysis (PrAMA) to measure ADAM10 and ADAM17 sheddase activities in cell and tissue lysates

by Yoneyama, Toshie, Gorry, Michael, Gaither-Davis, Autumn, Lin, Yan, Moss, Marcia L., Stabile, Laura P., Herman, James G., Vujanovic, Nikola L., Miller, Miles Aaron, Griffith, Linda G, Lauffenburger, Douglas A
Published 2018

Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies

by Dallas, Matthew, Stokes, Cynthia L., Maass, Christian Alexander, LaBarge, Matthew E, Shockley, Michael J, Valdez Macias, Jorge Luis, Geishecker, Emily R, Griffith, Linda G, Cirit, Murat
Published 2018

PiFlow: A biocompatible low-cost programmable dynamic flow pumping system utilizing a Raspberry Pi Zero and commercial piezoelectric pumps

by Kassis, Timothy, Perez, Paola M., Yang, Chloe J., Soenksen Martinez, Luis Ruben, Trumper, David L, Griffith, Linda G
Published 2018

A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties

by Wheeler, S. E., Stolz, D. B., Venkataramanan, R., Wells, A., Shepard, Nieman J., Clark, Abigail M, Young, Carissa L., Stockdale, Linda, Zhao, Weian, Lauffenburger, Douglas A, Griffith, Linda G
Published 2018

Local remodeling of synthetic extracellular matrix microenvironments by co-cultured endometrial epithelial and stromal cells enables long-term dynamic physiological function

by Isaacson, Keith B., Cook, Christi Dionne, Hill, Abby, Guo, Margaret G., Stockdale, Linda, Papps, Julia P, Lauffenburger, Douglas A, Griffith, Linda G
Published 2018

Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity

by Xu, Jinghai J., Hendriks, Bart S., Cosgrove, Benjamin D., King, Bracken Matheny, Hasan, Maya A., Alexopoulos, Leonidas G., Farazi, Paraskevi A., Sorger, Peter K., Tidor, Bruce, Griffith, Linda G., Lauffenburger, Douglas A.
Published 2011

On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks

by Ahrens, Caroline Chopko, Valdez Macias, Jorge Luis, Cook, Christi Dionne, Wang, Alex J-S, Brown, Alexander Thomas, Kumar, Manu Prajapati, Stockdale, Linda, Rothenberg, Daniel Abram, Renggli-Frey, Kasper, Gordon, Elizabeth A, Lauffenburger, Douglas A, Griffith, Linda G, White, Forest M.
Published 2018