Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation

by Agata Wesolowska-Andersen, Rikke Rejnholdt Jensen, Marta Pérez Alcántara, Nicola L. Beer, Claire Duff, Vibe Nylander, Matthew Gosden, Lorna Witty, Rory Bowden, Mark I. McCarthy, Mattias Hansson, Anna L. Gloyn, Christian Honore
Published 2020-01-01

Dynamics of the 4D genome during in vivo lineage specification and differentiation

by A. Marieke Oudelaar, Robert A. Beagrie, Matthew Gosden, Sara de Ornellas, Emily Georgiades, Jon Kerry, Daniel Hidalgo, Joana Carrelha, Arun Shivalingam, Afaf H. El-Sagheer, Jelena M. Telenius, Tom Brown, Veronica J. Buckle, Merav Socolovsky, Douglas R. Higgs, Jim R. Hughes
Published 2020-06-01

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia

by Sachith Mettananda, Chris A. Fisher, Deborah Hay, Mohsin Badat, Lynn Quek, Kevin Clark, Philip Hublitz, Damien Downes, Jon Kerry, Matthew Gosden, Jelena Telenius, Jackie A. Sloane-Stanley, Paula Faustino, Andreia Coelho, Jessica Doondeea, Batchimeg Usukhbayar, Paul Sopp, Jacqueline A. Sharpe, Jim R. Hughes, Paresh Vyas, Richard J. Gibbons, Douglas R. Higgs
Published 2017-09-01