SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells

by Bradley J. Toghill, Athanasios Saratzis, Peter J. Freeman, Nicolas Sylvius, UKAGS collaborators, Matthew J. Bown
Published 2018-03-01

Feature selection through validation and un-censoring of endovascular repair survival data for predicting the risk of re-intervention

by Omneya Attallah, Alan Karthikesalingam, Peter J. E. Holt, Matthew M. Thompson, Rob Sayers, Matthew J. Bown, Eddie C. Choke, Xianghong Ma
Published 2017-08-01

Screening women aged 65 years or over for abdominal aortic aneurysm: a modelling study and health economic evaluation

by Simon G Thompson, Matthew J Bown, Matthew J Glover, Edmund Jones, Katya L Masconi, Jonathan A Michaels, Janet T Powell, Pinar Ulug, Michael J Sweeting
Published 2018-08-01

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.

by Connor A Emdin, Mary E Haas, Amit V Khera, Krishna Aragam, Mark Chaffin, Derek Klarin, George Hindy, Lan Jiang, Wei-Qi Wei, Qiping Feng, Juha Karjalainen, Aki Havulinna, Tuomo Kiiskinen, Alexander Bick, Diego Ardissino, James G Wilson, Heribert Schunkert, Ruth McPherson, Hugh Watkins, Roberto Elosua, Matthew J Bown, Nilesh J Samani, Usman Baber, Jeanette Erdmann, Namrata Gupta, John Danesh, Danish Saleheen, Kyong-Mi Chang, Marijana Vujkovic, Ben Voight, Scott Damrauer, Julie Lynch, David Kaplan, Marina Serper, Philip Tsao, Million Veteran Program, Josep Mercader, Craig Hanis, Mark Daly, Joshua Denny, Stacey Gabriel, Sekar Kathiresan
Published 2020-04-01

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease

by Connor A. Emdin, Amit V. Khera, Mark Chaffin, Derek Klarin, Pradeep Natarajan, Krishna Aragam, Mary Haas, Alexander Bick, Seyedeh M. Zekavat, Akihiro Nomura, Diego Ardissino, James G. Wilson, Heribert Schunkert, Ruth McPherson, Hugh Watkins, Roberto Elosua, Matthew J. Bown, Nilesh J. Samani, Usman Baber, Jeanette Erdmann, Namrata Gupta, John Danesh, Daniel Chasman, Paul Ridker, Joshua Denny, Lisa Bastarache, Judith H. Lichtman, Gail D’Onofrio, Jennifer Mattera, John A. Spertus, Wayne H.-H. Sheu, Kent D. Taylor, Bruce M. Psaty, Stephen S. Rich, Wendy Post, Jerome I. Rotter, Yii-Der Ida Chen, Harlan Krumholz, Danish Saleheen, Stacey Gabriel, Sekar Kathiresan
Published 2018-04-01