Generation of an iPS cell line from bone marrow derived mesenchymal stromal cells from an elderly patient

by Matthias Megges, Sven Geissler, Georg N. Duda, James Adjaye
Published 2015-11-01

Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations.

by Alessandro Prigione, Amir M Hossini, Björn Lichtner, Akdes Serin, Beatrix Fauler, Matthias Megges, Rudi Lurz, Hans Lehrach, Eugenia Makrantonaki, Christos C Zouboulis, James Adjaye
Published 2011-01-01

Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature

by Lucas-Sebastian Spitzhorn, Matthias Megges, Wasco Wruck, Md Shaifur Rahman, Jörg Otte, Özer Degistirici, Roland Meisel, Rüdiger Volker Sorg, Richard O. C. Oreffo, James Adjaye
Published 2019-03-01