Engineered Tolerance: Tailoring Development, Function, and Antigen-Specificity of Regulatory T Cells

by Nicholas A. J. Dawson, Nicholas A. J. Dawson, Jens Vent-Schmidt, Megan K. Levings, Megan K. Levings
Published 2017-11-01

T-Cell Specificity Matters in IBD: Impaired IL10 Production Revealed by OmpC-Tetramers

by Laura Cook, PhD, Megan K. Levings, PhD
Published 2020-01-01

The Environment of Regulatory T Cell Biology: Cytokines, Metabolites and the Microbiome

by Romy Eleonora Hoeppli, Romy Eleonora Hoeppli, Dan eWu, Dan eWu, Laura eCook, Laura eCook, Megan K Levings, Megan K Levings
Published 2015-02-01

SHIP-deficient dendritic cells, unlike wild type dendritic cells, suppress T cell proliferation via a nitric oxide-independent mechanism.

by Frann Antignano, Melisa Hamilton, Scott Patterson, Victor Ho, Carla Cohen, Megan K Levings, Gerald Krystal
Published 2011-01-01

Inflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivo.

by Ekaterina Yurchenko, Marina T Shio, Tony C Huang, Maria Da Silva Martins, Moshe Szyf, Megan K Levings, Martin Olivier, Ciriaco A Piccirillo
Published 2012-01-01

Analysis of Flagellin-Specific Adaptive Immunity Reveals Links to Dysbiosis in Patients With Inflammatory Bowel DiseaseSummary

by Laura Cook, Daniel J. Lisko, May Q. Wong, Rosa V. Garcia, Megan E. Himmel, Ernest G. Seidman, Brian Bressler, Megan K. Levings, Theodore S. Steiner
Published 2020-01-01

CCL22 Prevents Rejection of Mouse Islet Allografts and Induces Donor-Specific Tolerance

by Joel Montane, Merce Obach, Sigrid Alvarez, Loraine Bischoff, Derek L. Dai, Galina Soukhatcheva, John J. Priatel, Gijs Hardenberg, Megan K. Levings, Rusung Tan, Paul C. Orban, C. Bruce Verchere
Published 2015-10-01