Increased autophagic sequestration in adaptor protein-3 deficient dendritic cells limits inflammasome activity and impairs antibacterial immunity.

by Adriana R Mantegazza, Meghan A Wynosky-Dolfi, Cierra N Casson, Ariel J Lefkovith, Sunny Shin, Igor E Brodsky, Michael S Marks
Published 2017-12-01

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

by Yves Dondelinger, Tom Delanghe, Dario Priem, Meghan A. Wynosky-Dolfi, Daniel Sorobetea, Diego Rojas-Rivera, Piero Giansanti, Ria Roelandt, Julia Gropengiesser, Klaus Ruckdeschel, Savvas N. Savvides, Albert J. R. Heck, Peter Vandenabeele, Igor E. Brodsky, Mathieu J. M. Bertrand
Published 2019-04-01

Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death.

by Naomi H Philip, Alexandra DeLaney, Lance W Peterson, Melanie Santos-Marrero, Jennifer T Grier, Yan Sun, Meghan A Wynosky-Dolfi, Erin E Zwack, Baofeng Hu, Tayla M Olsen, Anthony Rongvaux, Scott D Pope, Carolina B López, Andrew Oberst, Daniel P Beiting, Jorge Henao-Mejia, Igor E Brodsky
Published 2016-10-01