The dynamic interactome of human Aha1 upon Y223 phosphorylation

by Donald Wolfgeher, Diana M. Dunn, Mark R. Woodford, Dimitra Bourboulia, Gennady Bratslavsky, Mehdi Mollapour, Stephen J. Kron, Andrew W. Truman
Published 2015-12-01

Design of Disruptors of the Hsp90–Cdc37 Interface

by Ilda D’Annessa, Naama Hurwitz, Valentina Pirota, Giovanni Luca Beretta, Stella Tinelli, Mark Woodford, Mauro Freccero, Mehdi Mollapour, Nadia Zaffaroni, Haim Wolfson, Giorgio Colombo
Published 2020-01-01

Extracellular Phosphorylation of TIMP-2 by Secreted c-Src Tyrosine Kinase Controls MMP-2 Activity

by Javier Sánchez-Pozo, Alexander J. Baker-Williams, Mark R. Woodford, Renee Bullard, Beiyang Wei, Mehdi Mollapour, William G. Stetler-Stevenson, Gennady Bratslavsky, Dimitra Bourboulia
Published 2018-03-01

Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer

by Natela Dushukyan, Diana M. Dunn, Rebecca A. Sager, Mark R. Woodford, David R. Loiselle, Michael Daneshvar, Alexander J. Baker-Williams, John D. Chisholm, Andrew W. Truman, Cara K. Vaughan, Timothy A. Haystead, Gennady Bratslavsky, Dimitra Bourboulia, Mehdi Mollapour
Published 2017-11-01

Clinically Advanced Pheochromocytomas and Paragangliomas: A Comprehensive Genomic Profiling Study

by Gennady Bratslavsky, Ethan S. Sokol, Michael Daneshvar, Andrea Necchi, Oleg Shapiro, Joseph Jacob, Nick Liu, Tom S. Sanford, Ruben Pinkhasov, Hanan Goldberg, Jonathan K. Killian, Shakti Ramkissoon, Eric A. Severson, Richard S. P. Huang, Natalie Danziger, Mehdi Mollapour, Jeffrey S. Ross, Karel Pacak
Published 2021-07-01

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding

by Mark R. Woodford, Diana M. Dunn, Adam R. Blanden, Dante Capriotti, David Loiselle, Chrisostomos Prodromou, Barry Panaretou, Philip F. Hughes, Aaron Smith, Wendi Ackerman, Timothy A. Haystead, Stewart N. Loh, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour
Published 2016-06-01

Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis

by Alexander J. Baker-Williams, Fiza Hashmi, Marek A. Budzyński, Mark R. Woodford, Stephanie Gleicher, Samu V. Himanen, Alan M. Makedon, Derek Friedman, Stephanie Cortes, Sara Namek, William G. Stetler-Stevenson, Gennady Bratslavsky, Alaji Bah, Mehdi Mollapour, Lea Sistonen, Dimitra Bourboulia
Published 2019-08-01

Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90

by Rebecca A. Sager, Mark R. Woodford, Sarah J. Backe, Alan M. Makedon, Alexander J. Baker-Williams, Bryanna T. DiGregorio, David R. Loiselle, Timothy A. Haystead, Natasha E. Zachara, Chrisostomos Prodromou, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour
Published 2019-01-01

Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors

by Mark R. Woodford, Andrew W. Truman, Diana M. Dunn, Sandra M. Jensen, Richard Cotran, Renee Bullard, Mourad Abouelleil, Kristin Beebe, Donald Wolfgeher, Sara Wierzbicki, Dawn E. Post, Tiffany Caza, Shinji Tsutsumi, Barry Panaretou, Stephen J. Kron, Jane B. Trepel, Steve Landas, Chrisostomos Prodromou, Oleg Shapiro, William G. Stetler-Stevenson, Dimitra Bourboulia, Len Neckers, Gennady Bratslavsky, Mehdi Mollapour
Published 2016-02-01

c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells

by Diana M. Dunn, Mark R. Woodford, Andrew W. Truman, Sandra M. Jensen, Jacqualyn Schulman, Tiffany Caza, Taylor C. Remillard, David Loiselle, Donald Wolfgeher, Brian S.J. Blagg, Lucas Franco, Timothy A. Haystead, Soumya Daturpalli, Matthias P. Mayer, Jane B. Trepel, Rhodri M.L. Morgan, Chrisostomos Prodromou, Stephen J. Kron, Barry Panaretou, William G. Stetler-Stevenson, Steve K. Landas, Len Neckers, Gennady Bratslavsky, Dimitra Bourboulia, Mehdi Mollapour
Published 2015-08-01