Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome

by Syed-Rehan A. Hussain, Syed-Rehan A. Hussain, Mehmet E. Yalvac, Benedict Khoo, Sigrid Eckardt, K. John McLaughlin
Published 2021-04-01

Systemic delivery of AAVrh74.tMCK.hCAPN3 rescues the phenotype in a mouse model for LGMD2A/R1

by Zarife Sahenk, Burcak Ozes, Darren Murrey, Morgan Myers, Kyle Moss, Mehmet E. Yalvac, Alicia Ridgley, Lei Chen, Jerry R. Mendell
Published 2021-09-01

Impaired regeneration in calpain-3 null muscle is associated with perturbations in mTORC1 signaling and defective mitochondrial biogenesis

by Mehmet E. Yalvac, Jakkrit Amornvit, Cilwyn Braganza, Lei Chen, Syed-Rehan A. Hussain, Kimberly M. Shontz, Chrystal L. Montgomery, Kevin M. Flanigan, Sarah Lewis, Zarife Sahenk
Published 2017-12-01

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

by Florian Kopp, Mahmoud M Elguindy, Mehmet E Yalvac, He Zhang, Beibei Chen, Frank A Gillett, Sungyul Lee, Sushama Sivakumar, Hongtao Yu, Yang Xie, Prashant Mishra, Zarife Sahenk, Joshua T Mendell
Published 2019-02-01