The Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway.

by Ira Gordon, Melissa Paoloni, Christina Mazcko, Chand Khanna
Published 2009-10-01

A compendium of canine normal tissue gene expression.

by Joseph Briggs, Melissa Paoloni, Qing-Rong Chen, Xinyu Wen, Javed Khan, Chand Khanna
Published 2011-01-01

Comparative Gene Expression Analyses Identify Luminal and Basal Subtypes of Canine Invasive Urothelial Carcinoma That Mimic Patterns in Human Invasive Bladder Cancer.

by Deepika Dhawan, Melissa Paoloni, Shweta Shukradas, Dipanwita Roy Choudhury, Bruce A Craig, José A Ramos-Vara, Noah Hahn, Patty L Bonney, Chand Khanna, Deborah W Knapp
Published 2015-01-01

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.

by Melissa Paoloni, Christina Mazcko, Kimberly Selting, Susan Lana, Lisa Barber, Jeffrey Phillips, Katherine Skorupski, David Vail, Heather Wilson, Barbara Biller, Anne Avery, Matti Kiupel, Amy LeBlanc, Anna Bernhardt, Beatrice Brunkhorst, Robert Tighe, Chand Khanna
Published 2015-01-01

Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed) trials.

by Melissa Paoloni, Craig Webb, Christina Mazcko, David Cherba, William Hendricks, Susan Lana, E J Ehrhart, Brad Charles, Heather Fehling, Leena Kumar, David Vail, Michael Henson, Michael Childress, Barbara Kitchell, Christopher Kingsley, Seungchan Kim, Mark Neff, Barbara Davis, Chand Khanna, Jeffrey Trent
Published 2014-01-01

A Comparative Oncology Study of Iniparib Defines Its Pharmacokinetic Profile and Biological Activity in a Naturally-Occurring Canine Cancer Model.

by Corey Saba, Melissa Paoloni, Christina Mazcko, William Kisseberth, Jenna H Burton, Annette Smith, Heather Wilson-Robles, Sara Allstadt, David Vail, Carolyn Henry, Susan Lana, E J Ehrhart, Brad Charles, Michael Kent, Jessica Lawrence, Kristine Burgess, Antonella Borgatti, Steve Suter, Paul Woods, Ira Gordon, Patricia Vrignaud, Chand Khanna, Amy K LeBlanc
Published 2016-01-01

Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer

by Douglas Yee, Claudine Isaacs, Denise M. Wolf, Christina Yau, Paul Haluska, Karthik V. Giridhar, Andres Forero-Torres, A. Jo Chien, Anne M. Wallace, Lajos Pusztai, Kathy S. Albain, Erin D. Ellis, Heather Beckwith, Barbara B. Haley, Anthony D. Elias, Judy C. Boughey, Kathleen Kemmer, Rachel L. Yung, Paula R. Pohlmann, Debu Tripathy, Amy S. Clark, Hyo S. Han, Rita Nanda, Qamar J. Khan, Kristen K. Edmiston, Emanuel F. Petricoin, Erica Stringer-Reasor, Carla I. Falkson, Melanie Majure, Rita A. Mukhtar, Teresa L. Helsten, Stacy L. Moulder, Patricia A. Robinson, Julia D. Wulfkuhle, Lamorna Brown-Swigart, Meredith Buxton, Julia L. Clennell, Melissa Paoloni, Ashish Sanil, Scott Berry, Smita M. Asare, Amy Wilson, Gillian L. Hirst, Ruby Singhrao, Adam L. Asare, Jeffrey B. Matthews, Nola M. Hylton, Angela DeMichele, Michelle Melisko, Jane Perlmutter, Hope S. Rugo, W. Fraser Symmans, Laura J. van‘t Veer, Donald A. Berry, Laura J. Esserman
Published 2021-10-01