Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR.

by Mark M Yore, Arminja N Kettenbach, Michael B Sporn, Scott A Gerber, Karen T Liby
Published 2011-01-01

A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer.

by Jae Young So, Janice J Lin, Joseph Wahler, Karen T Liby, Michael B Sporn, Nanjoo Suh
Published 2014-01-01

NADPH oxidase limits innate immune responses in the lungs in mice.

by Brahm H Segal, Wei Han, Jennifer J Bushey, Myungsoo Joo, Zahida Bhatti, Joy Feminella, Carly G Dennis, R Robert Vethanayagam, Fiona E Yull, Maegan Capitano, Paul K Wallace, Hans Minderman, John W Christman, Michael B Sporn, Jefferson Chan, Donald C Vinh, Steven M Holland, Luigina R Romani, Sarah L Gaffen, Michael L Freeman, Timothy S Blackwell
Published 2010-03-01