The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma.

by Trupti Joshi, Latha P Ganesan, Carolyn Cheney, Michael C Ostrowski, Natarajan Muthusamy, John C Byrd, Susheela Tridandapani
Published 2009-01-01

MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation.

by Mohamed Kabbout, Duaa Dakhlallah, Sudarshana Sharma, Agnieszka Bronisz, Ruchika Srinivasan, Melissa Piper, Clay B Marsh, Michael C Ostrowski
Published 2014-01-01

PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis

by Shasha Yin, Liu Liu, Charles Brobbey, Viswanathan Palanisamy, Lauren E. Ball, Shaun K. Olsen, Michael C. Ostrowski, Wenjian Gan
Published 2021-06-01

Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis

by Yaoling Shu, Faizule Hassan, Vincenzo Coppola, Kedryn K. Baskin, Xianlin Han, Neil K. Mehta, Michael C. Ostrowski, Kamal D. Mehta
Published 2021-02-01

Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis.

by Ruchika Srinivasan, Tahera Zabuawala, Hong Huang, Jianying Zhang, Parul Gulati, Soledad Fernandez, J Colleen Karlo, Gary E Landreth, Gustavo Leone, Michael C Ostrowski
Published 2009-12-01

Pten regulates collagen fibrillogenesis by fibroblasts through SPARC.

by Caitlin E Jones, Joe T Sharick, Sheila E Colbert, Vasudha C Shukla, Joshua M Zent, Michael C Ostrowski, Samir N Ghadiali, Steven T Sizemore, Jennifer L Leight
Published 2021-01-01

TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy.

by Swarnali Acharyya, Sudarshana M Sharma, Alfred S Cheng, Katherine J Ladner, Wei He, William Kline, Huating Wang, Michael C Ostrowski, Tim H Huang, Denis C Guttridge
Published 2010-08-01

Cry protein crystals: a novel platform for protein delivery.

by Manoj S Nair, Marianne M Lee, Astrid Bonnegarde-Bernard, Julie A Wallace, Donald H Dean, Michael C Ostrowski, Richard W Burry, Prosper N Boyaka, Michael K Chan
Published 2015-01-01

Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland

by Caitlin E. Jones, Anisha M. Hammer, YouJin Cho, Gina M. Sizemore, Edna Cukierman, Lisa D. Yee, Samir N. Ghadiali, Michael C. Ostrowski, Jennifer L. Leight
Published 2019-01-01

Eomes partners with PU.1 and MITF to Regulate Transcription Factors Critical for osteoclast differentiation

by Heather A. Carey, Blake E. Hildreth, III, Devadoss J. Samuvel, Katie A. Thies, Thomas J. Rosol, Ramiro E. Toribio, Julia F. Charles, Michael C. Ostrowski, Sudarshana M. Sharma
Published 2019-01-01

Defining the Tumor Microenvironment by Integration of Immunohistochemistry and Extracellular Matrix Targeted Imaging Mass Spectrometry

by Denys Rujchanarong, Julia Lefler, Janet E. Saunders, Sarah Pippin, Laura Spruill, Jennifer R. Bethard, Lauren E. Ball, Anand S. Mehta, Richard R. Drake, Michael C. Ostrowski, Peggi M. Angel
Published 2021-09-01

Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.

by Jinghai Wu, Xin Liu, Sunayana G Nayak, Jason R Pitarresi, Maria C Cuitiño, Lianbo Yu, Blake E Hildreth, Katie A Thies, Daniel J Schilling, Soledad A Fernandez, Gustavo Leone, Michael C Ostrowski
Published 2017-01-01

Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo

by Hannah M. Komar, Gregory Serpa, Claire Kerscher, Erin Schwoegl, Thomas A. Mace, Ming Jin, Ming-Chen Yang, Ching-Shih Chen, Mark Bloomston, Michael C. Ostrowski, Phil A. Hart, Darwin L. Conwell, Gregory B. Lesinski
Published 2017-05-01

Protein Kinase C beta in the tumor microenvironment promotes mammary tumorigenesis

by Julie A Wallace, Jason R Pitarresi, Nandini eSharma, Marilly ePalettas, Maria C Cuitiño, Steven T Sizemore, Lianbo eYu, Allen eSanderlin, Thomas J Rosol, Kamal D. Mehta, Gina M Sizemore, Michael C Ostrowski
Published 2014-04-01

PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance

by Luke Russell, Jessica Swanner, Alena Cristina Jaime-Ramirez, Yufeng Wang, Alex Sprague, Yeshavanth Banasavadi-Siddegowda, Ji Young Yoo, Gina M. Sizemore, Raleigh Kladney, Jianying Zhang, Norman L. Lehman, Michael C Ostrowski, Bangxing Hong, Michael Caligiuri, Jianhua Yu, Balveen Kaur
Published 2018-11-01

Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation

by Maria C. Cuitiño, Thierry Pécot, Daokun Sun, Raleigh Kladney, Takayuki Okano-Uchida, Neelam Shinde, Resham Saeed, Antonio J. Perez-Castro, Amy Webb, Tom Liu, Soo In Bae, Linda Clijsters, Nicholas Selner, Vincenzo Coppola, Cynthia Timmers, Michael C. Ostrowski, Michele Pagano, Gustavo Leone
Published 2019-06-01

Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth

by Anisha M. Hammer, Gina M. Sizemore, Vasudha C. Shukla, Alex Avendano, Steven T. Sizemore, Jonathan J. Chang, Raleigh D. Kladney, Maria C. Cuitiño, Katie A. Thies, Quinn Verfurth, Arnab Chakravarti, Lisa D. Yee, Gustavo Leone, Jonathan W. Song, Samir N. Ghadiali, Michael C. Ostrowski
Published 2017-06-01

The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer

by Katie A. Thies, Matthew W. Cole, Rachel E. Schafer, Jonathan M. Spehar, Dillon S. Richardson, Sarah A. Steck, Manjusri Das, Arthur W. Lian, Alo Ray, Reena Shakya, Sue E. Knoblaugh, Cynthia D. Timmers, Michael C. Ostrowski, Arnab Chakravarti, Gina M. Sizemore, Steven T. Sizemore
Published 2021-06-01

Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.

by Julie A Wallace, Fu Li, Subhasree Balakrishnan, Carmen Z Cantemir-Stone, Thierry Pecot, Chelsea Martin, Raleigh D Kladney, Sudarshana M Sharma, Anthony J Trimboli, Soledad A Fernandez, Lianbo Yu, Thomas J Rosol, Paul C Stromberg, Robert Lesurf, Michael Hallett, Morag Park, Gustavo Leone, Michael C Ostrowski
Published 2013-01-01

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia

by Jason R. Pitarresi, Xin Liu, Sudarshana M. Sharma, Maria C. Cuitiño, Raleigh D. Kladney, Thomas A. Mace, Sydney Donohue, Sunayana G. Nayak, Chunjing Qu, James Lee, Sarah A. Woelke, Stefan Trela, Kyle LaPak, Lianbo Yu, Joseph McElroy, Thomas J. Rosol, Reena Shakya, Thomas Ludwig, Gregory B. Lesinski, Soledad A. Fernandez, Stephen F. Konieczny, Gustavo Leone, Jinghai Wu, Michael C. Ostrowski
Published 2016-09-01