MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations

by Md Helal U. Biswas, Sandra Almeida, Rodrigo Lopez-Gonzalez, Wenjie Mao, Zhijun Zhang, Anna Karydas, Michael D. Geschwind, Jacek Biernat, Eva-Maria Mandelkow, Kensuke Futai, Bruce L. Miller, Fen-Biao Gao
Published 2016-09-01

Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients

by Christina D. Orrù, Katrin Soldau, Christian Cordano, Jorge Llibre-Guerra, Ari J. Green, Henry Sanchez, Bradley R. Groveman, Steven D. Edland, Jiri G. Safar, Jonathan H. Lin, Byron Caughey, Michael D. Geschwind, Christina J. Sigurdson
Published 2018-11-01

Selective vulnerability to atrophy in sporadic Creutzfeldt‐Jakob disease

by Kyan Younes, Julio C. Rojas, Amy Wolf, Goh M. Sheng‐Yang, Matteo Paoletti, Gianina Toller, Eduardo Caverzasi, Maria Luisa Mandelli, Ignacio Illán‐Gala, Joel H. Kramer, Yann Cobigo, Bruce L. Miller, Howard J. Rosen, Michael D. Geschwind
Published 2021-06-01

An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy.

by Yun Li, Jason A Chen, Renee L Sears, Fuying Gao, Eric D Klein, Anna Karydas, Michael D Geschwind, Howard J Rosen, Adam L Boxer, Weilong Guo, Matteo Pellegrini, Steve Horvath, Bruce L Miller, Daniel H Geschwind, Giovanni Coppola
Published 2014-03-01

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

by Sandra Almeida, Zhijun Zhang, Giovanni Coppola, Wenjie Mao, Kensuke Futai, Anna Karydas, Michael D. Geschwind, M. Carmela Tartaglia, Fuying Gao, Davide Gianni, Miguel Sena-Esteves, Daniel H. Geschwind, Bruce L. Miller, Robert V. Farese, Jr., Fen-Biao Gao
Published 2012-10-01

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

by Sandra Almeida, Zhijun Zhang, Giovanni Coppola, Wenjie Mao, Kensuke Futai, Anna Karydas, Michael D. Geschwind, M. Carmela Tartaglia, Fuying Gao, Davide Gianni, Miguel Sena-Esteves, Daniel H. Geschwind, Bruce L. Miller, Robert V. Farese, Jr., Fen-Biao Gao
Published 2012-11-01

Multimodal MRI staging for tracking progression and clinical-imaging correlation in sporadic Creutzfeldt-Jakob disease

by Simone Sacco, Matteo Paoletti, Adam M. Staffaroni, Huicong Kang, Julio Rojas, Gabe Marx, Sheng-yang Goh, Maria Luisa Mandelli, Isabel E. Allen, Joel H. Kramer, Stefano Bastianello, Roland G. Henry, Howie.J. Rosen, Eduardo Caverzasi, Michael D. Geschwind
Published 2021-01-01

Baseline neuropsychological profiles in prion disease predict survival time

by Saranya E. Sundaram, Adam M. Staffaroni, Nicole C. Walker, Kaitlin B. Casaletto, Megan Casey, Aili Golubjatnikov, Stacy Metcalf, Kelly O’Leary, Katherine Wong, Kendra Benisano, Sven Forner, Marta Gonzalez Catalan, Isabel E. Allen, Howard J. Rosen, Joel H. Kramer, Michael D. Geschwind
Published 2020-09-01

Postural Tremor and Ataxia Progression in Spinocerebellar Ataxias

by Shi-Rui Gan, Jie Wang, Karla P. Figueroa, Stefan M. Pulst, Darya Tomishon, Danielle Lee, Susan Perlman, George Wilmot, Christopher ‎ M. Gomez, Jeremy Schmahmann, Henry Paulson, Vikramq G. Shakkottai, Sarah H. Ying, Theresa Zesiewicz, Khalaf Bushara, Michael D. Geschwind, Guangbin Xia, S. H. Subramony, Tetsuo Ashizawa, Sheng-Han Kuo
Published 2017-10-01

Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD

by Christina D. Orrú, Bradley R. Groveman, Aaron Foutz, Matilde Bongianni, Franco Cardone, Neil McKenzie, Audrey Culeux, Anna Poleggi, Katarina Grznarova, Daniela Perra, Michele Fiorini, Xiaoqin Liu, Anna Ladogana, Marco Sbriccoli, Andrew G. Hughson, Stéphane Haïk, Alison J. Green, Michael D. Geschwind, Maurizio Pocchiari, Jiri G. Safar, Gianluigi Zanusso, Byron Caughey
Published 2020-11-01