Increasing cell permeability of N-acetylglucosamine via 6-acetylation enhances capacity to suppress T-helper 1 (TH1)/TH17 responses and autoimmunity.

by Sung-Uk Lee, Carey F Li, Christie-Lynn Mortales, Judy Pawling, James W Dennis, Ani Grigorian, Michael Demetriou, Michael Demetriou
Published 2019-01-01

Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation

by Lindsey Araujo, Phillip Khim, Haik Mkhikian, Christie-Lynn Mortales, Michael Demetriou
Published 2017-01-01

N-Glycan Branching Decouples B Cell Innate and Adaptive Immunity to Control Inflammatory Demyelination

by Christie-Lynn Mortales, Sung-Uk Lee, Armen Manousadjian, Ken L. Hayama, Michael Demetriou
Published 2020-08-01

Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis

by Haik Mkhikian, Christie-Lynn Mortales, Raymond W Zhou, Khachik Khachikyan, Gang Wu, Stuart M Haslam, Patil Kavarian, Anne Dell, Michael Demetriou
Published 2016-06-01

Encoding asymmetry of the N-glycosylation motif facilitates glycoprotein evolution.

by Ryan Williams, Xiangyuan Ma, Ryan K Schott, Naveed Mohammad, Chi Yip Ho, Carey F Li, Belinda S W Chang, Michael Demetriou, James W Dennis
Published 2014-01-01

Effect of vitamin D supplementation on N‐glycan branching and cellular immunophenotypes in MS

by Priscilla Bäcker‐Koduah, Carmen Infante‐Duarte, Federico Ivaldi, Antonio Uccelli, Judith Bellmann‐Strobl, Klaus‐Dieter Wernecke, Michael Sy, Michael Demetriou, Jan Dörr, Friedemann Paul, Alexander Ulrich Brandt
Published 2020-09-01

Cell Surface N-Glycans Influence Electrophysiological Properties and Fate Potential of Neural Stem Cells

by Andrew R. Yale, Jamison L. Nourse, Kayla R. Lee, Syed N. Ahmed, Janahan Arulmoli, Alan Y.L. Jiang, Lisa P. McDonnell, Giovanni A. Botten, Abraham P. Lee, Edwin S. Monuki, Michael Demetriou, Lisa A. Flanagan
Published 2018-10-01

The Crossroads of Glycoscience, Infection, and Immunology

by Tanya R. McKitrick, Margaret E. Ackerman, Robert M. Anthony, Clay S. Bennett, Michael Demetriou, Gregory A. Hudalla, Katharina Ribbeck, Stefan Ruhl, Christina M. Woo, Loretta Yang, Seth J. Zost, Ronald L. Schnaar, Tamara L. Doering
Published 2021-09-01

Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer

by Yi Xing, Ananth Annapragada, Jose Conejo-Garcia, Conrad Russell Cruz, Shadmehr Demehri, Michael Demetriou, Levon Demirdjian, Mary Horowitz, Alan Hutson, Kathryn Kadash-Edmondson, Steven Lipkin, Claire McCarthy, Martin Morgan, Marcelo Pasquini, Stephen Schoenberger, Wenjuan Zha, Adekunle Odunsi
Published 2020-06-01