Urolithin A Protects Chondrocytes From Mechanical Overloading-Induced Injuries

by Yuchen He, Yuchen He, Lauren Yocum, Peter G Alexander, Michael J Jurczak, Hang Lin, Hang Lin, Hang Lin
Published 2021-06-01

Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway

by Dharendra Thapa, Michael W. Stoner, Manling Zhang, Bingxian Xie, Janet R. Manning, Danielle Guimaraes, Sruti Shiva, Michael J. Jurczak, Iain Scott
Published 2018-09-01

Hepatic insulin sensitivity is improved in high‐fat diet‐fed Park2 knockout mice in association with increased hepatic AMPK activation and reduced steatosis

by Lia R. Edmunds, Brydie R. Huckestein, Mario Kahn, Dongyan Zhang, Yanxia Chu, Yingze Zhang, Stacy G. Wendell, Gerald I. Shulman, Michael J. Jurczak
Published 2019-11-01

Nocturnal Hypoxia Improves Glucose Disposal, Decreases Mitochondrial Efficiency, and Increases Reactive Oxygen Species in the Muscle and Liver of C57BL/6J Mice Independent of Weigh...

by Simona Ioja, Srikanth Singamsetty, Catherine Corey, Lanping Guo, Faraaz Shah, Michael J. Jurczak, Bryan J. McVerry, Sruti Shiva, Christopher P. O’Donnell
Published 2018-01-01

ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content

by João Paulo G. Camporez, Shoichi Kanda, Max C. Petersen, François R. Jornayvaz, Varman T. Samuel, Sanjay Bhanot, Kitt Falk Petersen, Michael J. Jurczak, Gerald I. Shulman
Published 2015-03-01

Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance

by Lia R. Edmunds, Bingxian Xie, Amanda M. Mills, Brydie R. Huckestein, Ramya Undamatla, Anjana Murali, Martha M. Pangburn, James Martin, Ian Sipula, Brett A. Kaufman, Iain Scott, Michael J. Jurczak
Published 2020-11-01

Adropin reduces blood glucose levels in mice by limiting hepatic glucose production

by Dharendra Thapa, Bingxian Xie, Janet R. Manning, Manling Zhang, Michael W. Stoner, Brydie R. Huckestein, Lia R. Edmunds, Xueyang Zhang, Nikolaos L. Dedousis, Robert M. O'Doherty, Michael J. Jurczak, Iain Scott
Published 2019-04-01

Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs

by Dong Wang, Robert Hartman, Chao Han, Chao-ming Zhou, Brandon Couch, Matias Malkamaki, Vera Roginskaya, Bennett Van Houten, Steven J. Mullett, Stacy G. Wendell, Michael J. Jurczak, James Kang, Joon Lee, Gwendolyn Sowa, Nam Vo
Published 2021-05-01

Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance.

by Frances R Belmonte, Nikolaos Dedousis, Ian Sipula, Nikita A Desai, Aatur D Singhi, Yanxia Chu, Yingze Zhang, Sylvie Bannwarth, Véronique Paquis-Flucklinger, Lea Harrington, Sruti Shiva, Michael J Jurczak, Robert M O'Doherty, Brett A Kaufman
Published 2019-01-01

A big-data approach to understanding metabolic rate and response to obesity in laboratory mice

by June K Corrigan, Deepti Ramachandran, Yuchen He, Colin J Palmer, Michael J Jurczak, Rui Chen, Bingshan Li, Randall H Friedline, Jason K Kim, Jon J Ramsey, Louise Lantier, Owen P McGuinness, Mouse Metabolic Phenotyping Center Energy Balance Working Group, Alexander S Banks
Published 2020-05-01

MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels

by Arvindhan Nagarajan, Max C. Petersen, Ali R. Nasiri, Gina Butrico, Annie Fung, Hai-Bin Ruan, Romy Kursawe, Sonia Caprio, Jacques Thibodeau, Marie-Claude Bourgeois-Daigneault, Lisha Sun, Guangping Gao, Sanjay Bhanot, Michael J. Jurczak, Michael R. Green, Gerald I. Shulman, Narendra Wajapeyee
Published 2016-08-01

Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis

by Lisa Y. Beppu, Raja Gopal Reddy Mooli, Xiaoyao Qu, Giovanni J. Marrero, Christopher A. Finley, Allen N. Fooks, Zachary P. Mullen, Adolfo B. Frias Jr., Ian Sipula, Bingxian Xie, Katherine E. Helfrich, Simon C. Watkins, Amanda C. Poholek, Sadeesh K. Ramakrishnan, Michael J. Jurczak, Louise M. D’Cruz
Published 2021-02-01

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

by Josepmaria Argemi, Maria U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey, Joel P. Gue, Joaquin Cabezas, Juan J. Lozano, Derek Van Booven, Aaron Bell, Sheng Cao, Lawrence A. Vernetti, Juan P. Arab, Meritxell Ventura-Cots, Lia R. Edmunds, Constantino Fondevilla, Peter Stärkel, Laurent Dubuquoy, Alexandre Louvet, Gemma Odena, Juan L. Gomez, Tomas Aragon, Jose Altamirano, Juan Caballeria, Michael J. Jurczak, D. Lansing Taylor, Carmen Berasain, Claes Wahlestedt, Satdarshan P. Monga, Marsha Y. Morgan, Pau Sancho-Bru, Philippe Mathurin, Shinji Furuya, Carolin Lackner, Ivan Rusyn, Vijay H. Shah, Mark R. Thursz, Jelena Mann, Matias A. Avila, Ramon Bataller
Published 2019-07-01