Chronic stress and intestinal barrier dysfunction: Glucocorticoid receptor and transcription repressor HES1 regulate tight junction protein Claudin-1 promoter

by Gen Zheng, Gordon Victor Fon, Walter Meixner, Amy Creekmore, Ye Zong, Michael K. Dame, Justin Colacino, Priya H. Dedhia, Shuangsong Hong, John W. Wiley
Published 2017-07-01

Calcium-induced differentiation in normal human colonoid cultures: Cell-cell / cell-matrix adhesion, barrier formation and tissue integrity.

by Durga Attili, Shannon D McClintock, Areeba H Rizvi, Shailja Pandya, Humza Rehman, Daniyal M Nadeem, Aliah Richter, Dafydd Thomas, Michael K Dame, Danielle Kim Turgeon, James Varani, Muhammad N Aslam
Published 2019-01-01

Differentiation of human colon tissue in culture: Effects of calcium on trans-epithelial electrical resistance and tissue cohesive properties.

by Shannon D McClintock, Durga Attili, Michael K Dame, Aliah Richter, Sabrina S Silvestri, Maliha M Berner, Margaret S Bohm, Kateryna Karpoff, Caroline L McCarthy, Jason R Spence, James Varani, Muhammad N Aslam
Published 2020-01-01

Low-Level Mouse DNA in Conditioned Medium Generates False Positive Cross-Species Contamination Results in Human Organoid Cultures

by Margaret S. Bohm, Michael K. Dame, Joseph Boyd, Kevin Su, Angeline Wu, Durga Attili, Vi Chu, Justin A. Colacino, Justin A. Colacino, Justin A. Colacino, Jason R. Spence, Jason R. Spence, Jason R. Spence
Published 2020-11-01

Ulcerative Colitis-Derived Colonoid Culture: A Multi-Mineral-Approach to Improve Barrier Protein Expression

by Muhammad N. Aslam, Shannon D. McClintock, Durga Attili, Shailja Pandya, Humza Rehman, Daniyal M. Nadeem, Mohamed Ali H. Jawad-Makki, Areeba H. Rizvi, Maliha M. Berner, Michael K. Dame, Danielle Kim Turgeon, James Varani
Published 2020-11-01

Astrovirus replication in human intestinal enteroids reveals multi-cellular tropism and an intricate host innate immune landscape.

by Abimbola O Kolawole, Carmen Mirabelli, David R Hill, Sophia A Svoboda, Andrew B Janowski, Karla D Passalacqua, Benancio N Rodriguez, Michael K Dame, Pamela Freiden, Ryan P Berger, Diem-Lan Vu, Myra Hosmillo, Mary X D O'Riordan, Stacey Schultz-Cherry, Susana Guix, Jason R Spence, David Wang, Christiane E Wobus
Published 2019-10-01

Enteroendocrine Progenitor Cell–Enriched miR-7 Regulates Intestinal Epithelial Proliferation in an Xiap-Dependent MannerSummary

by Ajeet P. Singh, Yu-Han Hung, Michael T. Shanahan, Matt Kanke, Alessandro Bonfini, Michael K. Dame, Mandy Biraud, Bailey C.E. Peck, Oyebola O. Oyesola, John M. Freund, Rebecca L. Cubitt, Ennessa G. Curry, Liara M. Gonzalez, Gavin A. Bewick, Elia D. Tait-Wojno, Natasza A. Kurpios, Shengli Ding, Jason R. Spence, Christopher M. Dekaney, Nicolas Buchon, Praveen Sethupathy
Published 2020-01-01