Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells

by Charlotte Viant, Amelia Escolano, Spencer T. Chen, Michel C. Nussenzweig
Published 2021-06-01

Single-Cell Sorting of HBsAg-Binding Memory B Cells from Human Peripheral Blood Mononuclear Cells and Antibody Cloning

by Yunjiao Zhou, Zhenmi Liu, Zijun Wang, Qianqian Zhang, Christian T. Mayer, Till Schoofs, Michel C. Nussenzweig, Ype P. de Jong, Qiao Wang
Published 2020-12-01

Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses.

by Hugo Mouquet, Florian Klein, Johannes F Scheid, Malte Warncke, John Pietzsch, Thiago Y K Oliveira, Klara Velinzon, Michael S Seaman, Michel C Nussenzweig
Published 2011-01-01

Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development.

by Philipp C Rommel, David Bosque, Alexander D Gitlin, Gist F Croft, Nathaniel Heintz, Rafael Casellas, Michel C Nussenzweig, Skirmantas Kriaucionis, Davide F Robbiani
Published 2013-01-01

Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies

by Haoqing Wang, Harry B Gristick, Louise Scharf, Anthony P West Jr, Rachel P Galimidi, Michael S Seaman, Natalia T Freund, Michel C Nussenzweig, Pamela J Bjorkman
Published 2017-05-01

Characterization of Co-Formulated High-Concentration Broadly Neutralizing Anti-HIV-1 Monoclonal Antibodies for Subcutaneous Administration

by Vaneet K. Sharma, Bijay Misra, Kevin T. McManus, Sreenivas Avula, Kaliappanadar Nellaiappan, Marina Caskey, Jill Horowitz, Michel C. Nussenzweig, Michael S. Seaman, Indu Javeri, Antu K. Dey
Published 2020-07-01

RPA Accumulation during Class Switch Recombination Represents 5′–3′ DNA-End Resection during the S–G2/M Phase of the Cell Cycle

by Arito Yamane, Davide F. Robbiani, Wolfgang Resch, Anne Bothmer, Hirotaka Nakahashi, Thiago Oliveira, Philipp C. Rommel, Eric J. Brown, Andre Nussenzweig, Michel C. Nussenzweig, Rafael Casellas
Published 2013-01-01

Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope

by Christopher O. Barnes, Harry B. Gristick, Natalia T. Freund, Amelia Escolano, Artem Y. Lyubimov, Harald Hartweger, Anthony P. West, Aina E. Cohen, Michel C. Nussenzweig, Pamela J. Bjorkman
Published 2018-03-01

Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies

by David A. Garber, Debra R. Adams, Patricia Guenthner, James Mitchell, Kristen Kelley, Till Schoofs, Anna Gazumyan, Martha Nason, Michael S. Seaman, Janet McNicholl, Michel C. Nussenzweig, Walid Heneine
Published 2020-06-01

Structural basis for germline antibody recognition of HIV-1 immunogens

by Louise Scharf, Anthony P West Jr, Stuart A Sievers, Courtney Chen, Siduo Jiang, Han Gao, Matthew D Gray, Andrew T McGuire, Johannes F Scheid, Michel C Nussenzweig, Leonidas Stamatatos, Pamela J Bjorkman
Published 2016-03-01

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

by Louise Scharf, Johannes F. Scheid, Jeong Hyun Lee, Anthony P. West Jr., Courtney Chen, Han Gao, Priyanthi N.P. Gnanapragasam, René Mares, Michael S. Seaman, Andrew B. Ward, Michel C. Nussenzweig, Pamela J. Bjorkman
Published 2014-05-01

Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.

by Kshitij Wagh, Michael S Seaman, Marshall Zingg, Tomas Fitzsimons, Dan H Barouch, Dennis R Burton, Mark Connors, David D Ho, John R Mascola, Michel C Nussenzweig, Jeffrey Ravetch, Rajeev Gautam, Malcolm A Martin, David C Montefiori, Bette Korber
Published 2018-03-01

Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice

by David R. Martinez, Alexandra Schäfer, Sarah R. Leist, Dapeng Li, Kendra Gully, Boyd Yount, Joy Y. Feng, Elaine Bunyan, Danielle P. Porter, Tomas Cihlar, Stephanie A. Montgomery, Barton F. Haynes, Ralph S. Baric, Michel C. Nussenzweig, Timothy P. Sheahan
Published 2021-07-01

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice

by Andrew T. McGuire, Matthew D. Gray, Pia Dosenovic, Alexander D. Gitlin, Natalia T. Freund, John Petersen, Colin Correnti, William Johnsen, Robert Kegel, Andrew B. Stuart, Jolene Glenn, Michael S. Seaman, William R. Schief, Roland K. Strong, Michel C. Nussenzweig, Leonidas Stamatatos
Published 2016-02-01

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo.

by Natalia T Freund, Joshua A Horwitz, Lilian Nogueira, Stuart A Sievers, Louise Scharf, Johannes F Scheid, Anna Gazumyan, Cassie Liu, Klara Velinzon, Ariel Goldenthal, Rogier W Sanders, John P Moore, Pamela J Bjorkman, Michael S Seaman, Bruce D Walker, Florian Klein, Michel C Nussenzweig
Published 2015-10-01

Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

by Claudia A. Jette, Alexander A. Cohen, Priyanthi N.P. Gnanapragasam, Frauke Muecksch, Yu E. Lee, Kathryn E. Huey-Tubman, Fabian Schmidt, Theodora Hatziioannou, Paul D. Bieniasz, Michel C. Nussenzweig, Anthony P. West, Jr., Jennifer R. Keeffe, Pamela J. Bjorkman, Christopher O. Barnes
Published 2021-09-01

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

by Allison J. Greaney, Tyler N. Starr, Christopher O. Barnes, Yiska Weisblum, Fabian Schmidt, Marina Caskey, Christian Gaebler, Alice Cho, Marianna Agudelo, Shlomo Finkin, Zijun Wang, Daniel Poston, Frauke Muecksch, Theodora Hatziioannou, Paul D. Bieniasz, Davide F. Robbiani, Michel C. Nussenzweig, Pamela J. Bjorkman, Jesse D. Bloom
Published 2021-07-01

A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch

by Zijun Wang, Christopher O Barnes, Rajeev Gautam, Julio C Cetrulo Lorenzi, Christian T Mayer, Thiago Y Oliveira, Victor Ramos, Melissa Cipolla, Kristie M Gordon, Harry B Gristick, Anthony P West, Yoshiaki Nishimura, Henna Raina, Michael S Seaman, Anna Gazumyan, Malcolm Martin, Pamela J Bjorkman, Michel C Nussenzweig, Amelia Escolano
Published 2020-10-01

Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection.

by Kshitij Wagh, Tanmoy Bhattacharya, Carolyn Williamson, Alex Robles, Madeleine Bayne, Jetta Garrity, Michael Rist, Cecilia Rademeyer, Hyejin Yoon, Alan Lapedes, Hongmei Gao, Kelli Greene, Mark K Louder, Rui Kong, Salim Abdool Karim, Dennis R Burton, Dan H Barouch, Michel C Nussenzweig, John R Mascola, Lynn Morris, David C Montefiori, Bette Korber, Michael S Seaman
Published 2016-03-01

Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York

by Anthony P. West, Joel O. Wertheim, Jade C. Wang, Tetyana I. Vasylyeva, Jennifer L. Havens, Moinuddin A. Chowdhury, Edimarlyn Gonzalez, Courtney E. Fang, Steve S. Di Lonardo, Scott Hughes, Jennifer L. Rakeman, Henry H. Lee, Christopher O. Barnes, Priyanthi N. P. Gnanapragasam, Zhi Yang, Christian Gaebler, Marina Caskey, Michel C. Nussenzweig, Jennifer R. Keeffe, Pamela J. Bjorkman
Published 2021-08-01