Differential Neuroprotection by Cyclosporin A and FK506 Following Ischemia Corresponds with Differing Abilities to Inhibit Calcineurin and the Mitochondrial Permeability Transition

by Hiroyuki Uchino, Reiko Minamikawa-Tachino, Tibor Kristián, Guy Perkins, Michiko Narazaki, Bo K. Siesjö, Futoshi Shibasaki
Published 2002-08-01

Measurement of technetium-99m sestamibi signals in rats administered a mitochondrial uncoupler and in a rat model of heart failure.

by Akira Kawamoto, Takao Kato, Tetsuo Shioi, Junji Okuda, Tsuneaki Kawashima, Yodo Tamaki, Shinichiro Niizuma, Yohei Tanada, Genzou Takemura, Michiko Narazaki, Tetsuya Matsuda, Takeshi Kimura
Published 2015-01-01

Cardiac-specific inhibition of kinase activity in calcium/calmodulin-dependent protein kinase kinase-β leads to accelerated left ventricular remodeling and heart failure after tran...

by Shin Watanabe, Takahiro Horie, Kazuya Nagao, Yasuhide Kuwabara, Osamu Baba, Hitoo Nishi, Naoya Sowa, Michiko Narazaki, Tetsuya Matsuda, Genzou Takemura, Hiromichi Wada, Koji Hasegawa, Takeshi Kimura, Koh Ono
Published 2014-01-01

Persistent overexpression of phosphoglycerate mutase, a glycolytic enzyme, modifies energy metabolism and reduces stress resistance of heart in mice.

by Junji Okuda, Shinnichiro Niizuma, Tetsuo Shioi, Takao Kato, Yasutaka Inuzuka, Tsuneaki Kawashima, Yodo Tamaki, Akira Kawamoto, Yohei Tanada, Yoshitaka Iwanaga, Michiko Narazaki, Tetsuya Matsuda, Souichi Adachi, Tomoyoshi Soga, Genzou Takemura, Hiroshi Kondoh, Toru Kita, Takeshi Kimura
Published 2013-01-01