Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models

by Michiyo Iba, Changyoun Kim, Jazmin Florio, Michael Mante, Anthony Adame, Edward Rockenstein, Somin Kwon, Robert Rissman, Eliezer Masliah, Eliezer Masliah
Published 2020-03-01

α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration

by Hien T. Tran, Charlotte Hiu-Yan Chung, Michiyo Iba, Bin Zhang, John Q. Trojanowski, Kelvin C. Luk, Virginia M.Y. Lee
Published 2014-06-01

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

by Michiyo Iba, Changyoun Kim, Michelle Sallin, Somin Kwon, Anjali Verma, Cassia Overk, Robert A. Rissman, Ranjan Sen, Jyoti Misra Sen, Eliezer Masliah
Published 2020-07-01

P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating.

by Hiroki Takeuchi, Michiyo Iba, Haruhisa Inoue, Makoto Higuchi, Keizo Takao, Kayoko Tsukita, Yoshiko Karatsu, Yumiko Iwamoto, Tsuyoshi Miyakawa, Tetsuya Suhara, John Q Trojanowski, Virginia M-Y Lee, Ryosuke Takahashi
Published 2011-01-01

Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation

by Changyoun Kim, Brian Spencer, Edward Rockenstein, Hodaka Yamakado, Michael Mante, Anthony Adame, Jerel Adam Fields, Deborah Masliah, Michiyo Iba, He-Jin Lee, Robert A. Rissman, Seung-Jae Lee, Eliezer Masliah
Published 2018-08-01