Impact of vitamin D and vitamin D receptor TaqI polymorphism in primary human myoblasts

by Amarjit Saini, Linda Björkhem-Bergman, Johan Boström, Mats Lilja, Michael Melin, Karl Olsson, Lena Ekström, Peter Bergman, Mikael Altun, Eric Rullman, Thomas Gustafsson
Published 2019-07-01

The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.

by Mikael Altun, Thomas S Walter, Holger B Kramer, Patrick Herr, Alexander Iphöfer, Johan Boström, Yael David, Alia Komsany, Nicola Ternette, Ami Navon, David I Stuart, Jingshan Ren, Benedikt M Kessler
Published 2015-01-01

The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation

by Yaser Heshmati, Shabnam Kharazi, Gözde Türköz, David Chang, Esmat Kamali Dolatabadi, Johan Boström, Aleksandra Krstic, Theodora Boukoura, Emma Wagner, Nadir Kadri, Robert Månsson, Mikael Altun, Hong Qian, Julian Walfridsson
Published 2018-07-01

Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells.

by Johan Boström, Zuzana Sramkova, Alena Salašová, Helena Johard, Diana Mahdessian, Radek Fedr, Carolyn Marks, Jiřina Medalová, Karel Souček, Emma Lundberg, Sten Linnarsson, Vítězslav Bryja, Petra Sekyrova, Mikael Altun, Michael Andäng
Published 2017-01-01

Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound

by Tatiana A. Giovannucci, Florian A. Salomons, Martin Haraldsson, Lotta H. M. Elfman, Malin Wickström, Patrick Young, Thomas Lundbäck, Jürgen Eirich, Mikael Altun, Rozbeh Jafari, Anna-Lena Gustavsson, John Inge Johnsen, Nico P. Dantuma
Published 2021-10-01

Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

by Kumar Sanjiv, Anna Hagenkort, José Manuel Calderón-Montaño, Tobias Koolmeister, Philip M. Reaper, Oliver Mortusewicz, Sylvain A. Jacques, Raoul V. Kuiper, Niklas Schultz, Martin Scobie, Peter A. Charlton, John R. Pollard, Ulrika Warpman Berglund, Mikael Altun, Thomas Helleday
Published 2016-12-01

Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

by Kumar Sanjiv, Anna Hagenkort, José Manuel Calderón-Montaño, Tobias Koolmeister, Philip M. Reaper, Oliver Mortusewicz, Sylvain A. Jacques, Raoul V. Kuiper, Niklas Schultz, Martin Scobie, Peter A. Charlton, John R. Pollard, Ulrika Warpman Berglund, Mikael Altun, Thomas Helleday
Published 2016-01-01