Lessons learned from the DAPA-HF trial concerning the mechanisms of benefit of SGLT2 inhibitors on heart failure events in the context of other large-scale trials nearing completio...

by Milton Packer
Published 2019-10-01

Disease–treatment interactions in the management of patients with obesity and diabetes who have atrial fibrillation: the potential mediating influence of epicardial adipose tissue...

by Milton Packer
Published 2019-09-01

Autophagy-dependent and -independent modulation of oxidative and organellar stress in the diabetic heart by glucose-lowering drugs

by Milton Packer
Published 2020-05-01

Have dipeptidyl peptidase-4 inhibitors ameliorated the vascular complications of type 2 diabetes in large-scale trials? The potential confounding effect of stem-cell chemokines

by Milton Packer
Published 2018-01-01

Link Between Synovial and Myocardial Inflammation: Conceptual Framework to Explain the Pathogenesis of Heart Failure with Preserved Ejection Fraction in Patients with Systemic Rheu...

by Milton Packer
Published 2020-05-01

Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis

by Hao Tang, Salwa Sebti, Rossella Titone, Yunyun Zhou, Ciro Isidoro, Theodora S. Ross, Hanina Hibshoosh, Guanghua Xiao, Milton Packer, Yang Xie, Beth Levine
Published 2015-03-01

Effects of Sacubitril/Valsartan on Serum Lipids in Heart Failure With Preserved Ejection Fraction

by Senthil Selvaraj, Brian L. Claggett, Milton Packer, Faiez Zannad, Inder S. Anand, Burkert Pieske, Ziqiang Zhao, Victor C. Shi, Martin P. Lefkowitz, John J. V. McMurray, Scott D. Solomon
Published 2021-09-01

Relationship between duration of heart failure, patient characteristics, outcomes, and effect of therapy in PARADIGM‐HF

by Su E. Yeoh, Pooja Dewan, Akshay S. Desai, Scott D. Solomon, Jean L. Rouleau, Marty Lefkowitz, Adel Rizkala, Karl Swedberg, Michael R. Zile, Pardeep S. Jhund, Milton Packer, John J.V. McMurray
Published 2020-12-01

Clinical Characteristics and Outcomes of Patients With Heart Failure With Reduced Ejection Fraction and Chronic Obstructive Pulmonary Disease: Insights From PARADIGM‐HF

by Solmaz Ehteshami‐Afshar, Leanne Mooney, Pooja Dewan, Akshay S. Desai, Ninian N. Lang, Martin P. Lefkowitz, Mark C. Petrie, Adel R. Rizkala, Jean L. Rouleau, Scott D. Solomon, Karl Swedberg, Victor C. Shi, Michael R. Zile, Milton Packer, John J. V. McMurray, Pardeep S. Jhund, Nathaniel M. Hawkins
Published 2021-02-01

Unraveling the Molecular Mechanism of Action of Empagliflozin in Heart Failure With Reduced Ejection Fraction With or Without Diabetes

by Oriol Iborra-Egea, MSc, Evelyn Santiago-Vacas, MD, Salva R. Yurista, MD, Josep Lupón, MD, PhD, Milton Packer, MD, Stephane Heymans, MD, Faiez Zannad, MD, Javed Butler, MD, Domingo Pascual-Figal, MD, Antonio Lax, PhD, Julio Núñez, MD, PhD, Rudolf A. de Boer, MD, PhD, Antoni Bayés-Genís, MD, PhD
Published 2019-11-01