An internal thioester in a pathogen surface protein mediates covalent host binding

by Miriam Walden, John M Edwards, Aleksandra M Dziewulska, Rene Bergmann, Gerhard Saalbach, Su-Yin Kan, Ona K Miller, Miriam Weckener, Rosemary J Jackson, Sally L Shirran, Catherine H Botting, Gordon J Florence, Manfred Rohde, Mark J Banfield, Ulrich Schwarz-Linek
Published 2015-06-01

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

by Jiandong Huo, Halina Mikolajek, Audrey Le Bas, Jordan J. Clark, Parul Sharma, Anja Kipar, Joshua Dormon, Chelsea Norman, Miriam Weckener, Daniel K. Clare, Peter J. Harrison, Julia A. Tree, Karen R. Buttigieg, Francisco J. Salguero, Robert Watson, Daniel Knott, Oliver Carnell, Didier Ngabo, Michael J. Elmore, Susan Fotheringham, Adam Harding, Lucile Moynié, Philip N. Ward, Maud Dumoux, Tessa Prince, Yper Hall, Julian A. Hiscox, Andrew Owen, William James, Miles W. Carroll, James P. Stewart, James H. Naismith, Raymond J. Owens
Published 2021-09-01