Activity of Birinapant, a SMAC Mimetic Compound, Alone or in Combination in NSCLCs With Different Mutations

by Marika Colombo, Mirko Marabese, Giulia Vargiu, Massimo Broggini, Elisa Caiola
Published 2020-10-01

Glutaminase Inhibition on NSCLC Depends on Extracellular Alanine Exploitation

by Elisa Caiola, Marika Colombo, Giovanna Sestito, Monica Lupi, Mirko Marabese, Roberta Pastorelli, Massimo Broggini, Laura Brunelli
Published 2020-07-01

Co-occurring KRAS mutation/LKB1 loss in non-small cell lung cancer cells results in enhanced metabolic activity susceptible to caloric restriction: an in vitro integrated multileve...

by Elisa Caiola, Francesca Falcetta, Silvia Giordano, Mirko Marabese, Marina C. Garassino, Massimo Broggini, Roberta Pastorelli, Laura Brunelli
Published 2018-12-01

Randomised phase II trial (NCT00637975) evaluating activity and toxicity of two different escalating strategies for pregabalin and oxycodone combination therapy for neuropathic pai...

by Marina Chiara Garassino, Sheila Piva, Nicla La Verde, Ilaria Spagnoletti, Vittorio Iorno, Claudia Carbone, Antonio Febbraro, Anna Bianchi, Annalisa Bramati, Anna Moretti, Monica Ganzinelli, Mirko Marabese, Marta Gentili, Valter Torri, Gabriella Farina
Published 2013-01-01

LKB1 mutations are not associated with the efficacy of first-line and second-line chemotherapy in patients with advanced non-small-cell lung cancer (NSCLC): a post hoc analysis of...

by Adele Busico, Valter Torri, Giulia Galli, Giuseppe Lo Russo, Claudia Proto, Monica Ganzinelli, Claudio Vernieri, Diego Signorelli, Eliana Rulli, Gabriella Farina, Anna Cecilia Bettini, Claudia Bareggi, Lorenzo Rosso, Massimo Moro, Stefano Indraccolo, Gabriella Sozzi, Mirko Marabese, Broggini Massimo, Marina C. Garassino
Published 2020-05-01

Predicting the Role of DNA Polymerase β Alone or with <i>KRAS</i> Mutations in Advanced NSCLC Patients Receiving Platinum-Based Chemotherapy

by Maria Francesca Alvisi, Monica Ganzinelli, Helena Linardou, Elisa Caiola, Giuseppe Lo Russo, Fabiana Letizia Cecere, Anna Cecilia Bettini, Amanda Psyrri, Michele Milella, Eliana Rulli, Alessandra Fabbri, Marcella De Maglie, Pierpaolo Romanelli, Samuel Murray, Gloriana Ndembe, Massimo Broggini, Marina Chiara Garassino, Mirko Marabese
Published 2020-07-01

Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models

by Anais Del Curatolo, Fabiana Conciatori, Ursula Cesta Incani, Chiara Bazzichetto, Italia Falcone, Vincenzo Corbo, Sabrina D’Agosto, Adriana Eramo, Giovanni Sette, Isabella Sperduti, Teresa De Luca, Mirko Marabese, Senji Shirasawa, Ruggero De Maria, Aldo Scarpa, Massimo Broggini, Donatella Del Bufalo, Francesco Cognetti, Michele Milella, Ludovica Ciuffreda
Published 2018-07-01