Regulatory T Cells Maintain Peripheral Tolerance to Islet Allografts Induced by Intrathymic Injection of MHC Class I Allopeptides

by David V. Saborio, Nepal C. Chowdhury, Ming-Xing Jin, Anil Chandraker, Mohamed H. Sayegh, Soji F. Oluwole M.D.
Published 1999-07-01

CD160Ig fusion protein targets a novel costimulatory pathway and prolongs allograft survival.

by Francesca D'Addio, Takuya Ueno, Michael Clarkson, Baogong Zhu, Andrea Vergani, Gordon J Freeman, Mohamed H Sayegh, Mohammed Javeed I Ansari, Paolo Fiorina, Antje Habicht
Published 2013-01-01

Live images of donor Dendritic Cells trafficking via CX3CR1 pathway

by Takuya Ueno, Pilhan Kim, Martina M McGrath, Melissa Y Yeung, Tetsunosuke Shimizu, Keehoon Jung, Mohamed H Sayegh, Anil K Chandraker, Reza Abdi, Seok H Yun
Published 2016-10-01

Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes.

by Nora M Kochupurakkal, Annie J Kruger, Sudipta Tripathi, Bing Zhu, La Tonya Adams, Daniel B Rainbow, Aldo Rossini, Dale L Greiner, Mohamed H Sayegh, Linda S Wicker, Indira Guleria
Published 2014-01-01

The Limits of Linked Suppression for Regulatory T cells

by Toshiro eIto, Akira eYamada, Ibrahim eBatal, Melissa Y Yeung, Martina eMcGrath, Mohamed H. Sayegh, Anil eChandraker, Takuya eUeno, Takuya eUeno
Published 2016-03-01

TIM4 Regulates the Anti-Islet Th2 Alloimmune Response

by Andrea Vergani, Francesca Gatti, Kang M. Lee, Francesca D'addio, Sara Tezza, Melissa Chin, Roberto Bassi, Ze Tian, Erxi Wu, Paola Maffi, Moufida Ben Nasr, James I. Kim, Antonio Secchi, James F. Markmann, David M. Rothstein, Laurence A. Turka, Mohamed H. Sayegh, Paolo Fiorina M.D., Ph.D
Published 2015-08-01

ABCB5 Identifies Immunoregulatory Dermal Cells

by Tobias Schatton, Jun Yang, Sonja Kleffel, Mayuko Uehara, Steven R. Barthel, Christoph Schlapbach, Qian Zhan, Stephen Dudeney, Hansgeorg Mueller, Nayoung Lee, Juliane C. de Vries, Barbara Meier, Seppe Vander Beken, Mark A. Kluth, Christoph Ganss, Arlene H. Sharpe, Ana Maria Waaga-Gasser, Mohamed H. Sayegh, Reza Abdi, Karin Scharffetter-Kochanek, George F. Murphy, Thomas S. Kupper, Natasha Y. Frank, Markus H. Frank
Published 2015-09-01