HOW BLOCKCHAIN HELPS TO ENHANCE HEALTHCARE QUALITY: POTENTIAL IMPACT ON CRISIS SITUATIONS LIKE COVID-19 PANDEMIC

by Abdulmajeed Mohammed M Alanazi
Published 2020-12-01

Mechanistic interaction study of 5,6-Dichloro-2-[2-(pyridin-2-yl)ethyl]isoindoline-1,3-dione with bovine serum albumin by spectroscopic and molecular docking approaches

by Mohammed M. Alanazi, Abdulrahman A. Almehizia, Ahmed H. Bakheit, Nawaf A. Alsaif, Hamad M. Alkahtani, Tanveer A. Wani
Published 2019-03-01

Synthesis, antitumor activity, and molecular docking study of 2-cyclopentyloxyanisole derivatives: mechanistic study of enzyme inhibition

by Walaa M. El-Husseiny, Magda A.-A. El-Sayed, Adel S. El-Azab, Nawaf A. AlSaif, Mohammed M. Alanazi, Alaa A.-M. Abdel-Aziz
Published 2020-01-01

Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers

by Mohammed M. Alanazi, Ibrahim H. Eissa, Nawaf A. Alsaif, Ahmad J. Obaidullah, Wael A. Alanazi, Abdullah F. Alasmari, Hussam Albassam, Hazem Elkady, Alaa Elwan
Published 2021-01-01

Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers

by Nawaf A. Alsaif, Mohammed S. Taghour, Mohammed M. Alanazi, Ahmad J. Obaidullah, Abdulrahman A. Al-Mehizia, Manal M. Alanazi, Saleh Aldawas, Alaa Elwan, Hazem Elkady
Published 2021-01-01

Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies

by Mohammed M. Alanazi, Alaa Elwan, Nawaf A. Alsaif, Ahmad J. Obaidullah, Hamad M. Alkahtani, Abdulrahman A. Al-Mehizia, Sultan M. Alsubaie, Mohammed S. Taghour, Ibrahim H. Eissa
Published 2021-01-01

A New CDK2 Inhibitor with 3-Hydrazonoindolin-2-One Scaffold Endowed with Anti-Breast Cancer Activity: Design, Synthesis, Biological Evaluation, and In Silico Insights

by Mohammad M. Al-Sanea, Ahmad J. Obaidullah, Mohamed E. Shaker, Garri Chilingaryan, Mohammed M. Alanazi, Nawaf A. Alsaif, Hamad M. Alkahtani, Sultan A. Alsubaie, Mohamed A. Abdelgawad
Published 2021-01-01

Deeper Insights on <i>Cnesmone javanica</i> Blume Leaves Extract: Chemical Profiles, Biological Attributes, Network Pharmacology and Molecular Docking

by Ahmad J. Obaidullah, Mohammed M. Alanazi, Nawaf A. Alsaif, Wael A. Mahdi, Omer I. Fantoukh, Abu Montakim Tareq, Saad Ahmed Sami, Ali M. Alqahtani, Talha Bin Emran
Published 2021-04-01

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors

by Adel S. El-Azab, Alaa A.-M. Abdel-Aziz, Silvia Bua, Alessio Nocentini, Nawaf A. AlSaif, Mohammed M. Alanazi, Manal A. El-Gendy, Hany E. A. Ahmed, Claudiu T. Supuran
Published 2020-01-01

Protective effect of diosmin against doxorubicin-induced nephrotoxicity

by Nemat Ali, Abdullah F. AlAsmari, Faisal Imam, Mohammad Z. Ahmed, Faleh Alqahtani, Metab Alharbi, Mohammed AlSwayyed, Fawaz AlAsmari, Mohammed Alasmari, Abdulrahman Alshammari, Omer I. Fantoukh, Mohammed M. Alanazi
Published 2021-08-01

Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking...

by Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Nawaf A. AlSaif, Mohammed M. Alanazi, Manal A. El-Gendy, Ahmad J. Obaidullah, Hamad M. Alkahtani, Abdulrahman A. Almehizia, Ibrahim A. Al-Suwaidan
Published 2020-01-01

Elucidation of the Molecular Mechanisms Underlying Sorafenib-Induced Hepatotoxicity

by Abdullah F. AlAsmari, Nemat Ali, Fawaz AlAsmari, Wael A. AlAnazi, Faleh Alqahtani, Metab Alharbi, Farraj M. Alotaibi, Abdullah A. Aldossari, Mohammed AlSwayyed, Mohammed M. Alanazi, Ali A. Alshamrani
Published 2020-01-01

Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5,5-diphenylimidazolidine-2,4-dione derivatives: Molecular docking studies

by Hamad M. Alkahtani, Mohammed M. Alanazi, Fadilah Sfouq Aleanizy, Fulwah Yahya Alqahtani, Ali Alhoshani, Fawaz E. Alanazi, Abdulrahman A. Almehizia, Ashraf N. Abdalla, Mashael G. Alanazi, Adel S. El-Azab, Alaa A.-M. Abdel-Aziz
Published 2019-07-01

Liraglutide attenuates gefitinib-induced cardiotoxicity and promotes cardioprotection through the regulation of MAPK/NF-κB signaling pathways

by Abdullah F. AlAsmari, Nemat Ali, Fawaz AlAsmari, Wael A. AlAnazi, Musaad A. AlShammari, Naif O. Al-Harbi, Ali Alhoshani, Homood M. As Sobeai, Mohammed AlSwayyed, Mohammed M. AlAnazi, Nader S. AlGhamdi
Published 2020-04-01