Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1.

by Brian Onken, Monica Driscoll
Published 2010-01-01

Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension.

by Brian Onken, Natallia Kalinava, Monica Driscoll
Published 2020-08-01

Necrotic Neurodegeneration in Caenorhabditis Elegans

by Keli Xu, Beate Gerstbrein, Monica Driscoll
Published 2001-01-01

Execution of Necrotic-Like Cell Death in Caenorhabditis elegans Requires Cathepsin D Activity

by Nektarios Tavernarakis, Keli Xu, Monica Driscoll
Published 2001-01-01

Sequence relationships among C. elegans, D. melanogaster and human microRNAs highlight the extensive conservation of microRNAs in biology.

by Carolina Ibáñez-Ventoso, Mehul Vora, Monica Driscoll
Published 2008-07-01

Q&A: Trash talk: disposal and remote degradation of neuronal garbage

by Meghan Lee Arnold, Ilija Melentijevic, Anna Joelle Smart, Monica Driscoll
Published 2018-01-01

Single swim sessions in C. elegans induce key features of mammalian exercise

by Ricardo Laranjeiro, Girish Harinath, Daniel Burke, Bart P. Braeckman, Monica Driscoll
Published 2017-04-01

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans.

by Malene Hansen, Abha Chandra, Laura L Mitic, Brian Onken, Monica Driscoll, Cynthia Kenyon
Published 2008-02-01

CeleST: computer vision software for quantitative analysis of C. elegans swim behavior reveals novel features of locomotion.

by Christophe Restif, Carolina Ibáñez-Ventoso, Mehul M Vora, Suzhen Guo, Dimitris Metaxas, Monica Driscoll
Published 2014-07-01

Phytoecdysteroid-enriched quinoa seed leachate enhances healthspan and mitochondrial metabolism in Caenorhabditis elegans

by Brittany L. Graf, Shaunak Kamat, Kuan Yu Cheong, Slavko Komarnytsky, Monica Driscoll, Rong Di
Published 2017-10-01

Deletion of microRNA-80 activates dietary restriction to extend C. elegans healthspan and lifespan.

by Mehul Vora, Mitalie Shah, Silvana Ostafi, Brian Onken, Jian Xue, Julie Zhouli Ni, Sam Gu, Monica Driscoll
Published 2013-08-01

Swimming Exercise and Transient Food Deprivation in Caenorhabditis elegans Promote Mitochondrial Maintenance and Protect Against Chemical-Induced Mitotoxicity

by Jessica H. Hartman, Latasha L. Smith, Kacy L. Gordon, Ricardo Laranjeiro, Monica Driscoll, David R. Sherwood, Joel N. Meyer
Published 2018-05-01

Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans

by Ricardo Laranjeiro, Girish Harinath, Amelia K. Pollard, Christopher J. Gaffney, Colleen S. Deane, Siva A. Vanapalli, Timothy Etheridge, Nathaniel J. Szewczyk, Monica Driscoll
Published 2021-02-01

The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity

by Francis R. G. Amrit, Nikki Naim, Ramesh Ratnappan, Julia Loose, Carter Mason, Laura Steenberge, Brooke T. McClendon, Guoqiang Wang, Monica Driscoll, Judith L. Yanowitz, Arjumand Ghazi
Published 2019-07-01

The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans.

by Berangere Pinan-Lucarre, Christopher V Gabel, Christopher P Reina, S Elizabeth Hulme, Sergey S Shevkoplyas, R Daniel Slone, Jian Xue, Yujie Qiao, Sarah Weisberg, Kevin Roodhouse, Lin Sun, George M Whitesides, Aravinthan Samuel, Monica Driscoll
Published 2012-01-01

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

by Mark Lucanic, W. Todd Plummer, Esteban Chen, Jailynn Harke, Anna C. Foulger, Brian Onken, Anna L. Coleman-Hulbert, Kathleen J. Dumas, Suzhen Guo, Erik Johnson, Dipa Bhaumik, Jian Xue, Anna B. Crist, Michael P. Presley, Girish Harinath, Christine A. Sedore, Manish Chamoli, Shaunak Kamat, Michelle K. Chen, Suzanne Angeli, Christina Chang, John H. Willis, Daniel Edgar, Mary Anne Royal, Elizabeth A. Chao, Shobhna Patel, Theo Garrett, Carolina Ibanez-Ventoso, June Hope, Jason L Kish, Max Guo, Gordon J. Lithgow, Monica Driscoll, Patrick C. Phillips
Published 2017-02-01