Cell Adhesion in Cancer

by Eok-Soo Oh, Motoharu Seiki, Martin Gotte, Jun Chung
Published 2012-01-01

Turnover of Focal Adhesions and Cancer Cell Migration

by Makoto Nagano, Daisuke Hoshino, Naohiko Koshikawa, Toshifumi Akizawa, Motoharu Seiki
Published 2012-01-01

Correction: Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia.

by Ayako Watanabe, Daisuke Hoshino, Naohiko Koshikawa, Motoharu Seiki, Takashi Suzuki, Kazuhisa Ichikawa
Published 2013-06-01

Critical role of transient activity of MT1-MMP for ECM degradation in invadopodia.

by Ayako Watanabe, Daisuke Hoshino, Naohiko Koshikawa, Motoharu Seiki, Takashi Suzuki, Kazuhisa Ichikawa
Published 2013-01-01

Genetic screening of new genes responsible for cellular adaptation to hypoxia using a genome-wide shRNA library.

by Seiko Yoshino, Toshiro Hara, Jane S Weng, Yuka Takahashi, Motoharu Seiki, Takeharu Sakamoto
Published 2012-01-01

The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.

by Daisuke Hoshino, Makoto Nagano, Anri Saitoh, Naohiko Koshikawa, Takashi Suzuki, Motoharu Seiki
Published 2013-01-01

Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies.

by Daisuke Hoshino, Naohiko Koshikawa, Takashi Suzuki, Vito Quaranta, Alissa M Weaver, Motoharu Seiki, Kazuhisa Ichikawa
Published 2012-01-01

Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages

by Takayuki Uematsu, Kohsuke Tsuchiya, Noritada Kobayashi, Motoharu Seiki, Jun-ichiro Inoue, Shuichi Kaneko, Takeharu Sakamoto
Published 2021-04-01

Mint3 is dispensable for pancreatic and kidney functions in mice

by Yoohwa Chung, Yurika Saitoh, Tetsuro Hayashi, Yuya Fukui, Nobuo Terada, Motoharu Seiki, Yoshinori Murakami, Takeharu Sakamoto
Published 2020-12-01

Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review

by Hiroshi Yasuda, Masatoshi Nakagawa, Hirofumi Kiyokawa, Eisaku Yoshida, Toru Yoshimura, Naohiko Koshikawa, Fumio Itoh, Motoharu Seiki
Published 2019-01-01

Investigation of a MMP-2 activity-dependent anchoring probe for nuclear imaging of cancer.

by Takashi Temma, Hirofumi Hanaoka, Aki Yonezawa, Naoya Kondo, Kohei Sano, Takeharu Sakamoto, Motoharu Seiki, Masahiro Ono, Hideo Saji
Published 2014-01-01

Development of a fully automated chemiluminescence immunoassay for urine monomeric laminin-γ2 as a promising diagnostic tool of non-muscle invasive bladder cancer

by Masatoshi Nakagawa, Takashi Karashima, Masayuki Kamada, Eisaku Yoshida, Toru Yoshimura, Masanori Nojima, Keiji Inoue, Taro Shuin, Motoharu Seiki, Naohiko Koshikawa
Published 2017-10-01

Detection of the heterogeneous O-glycosylation profile of MT1-MMP expressed in cancer cells by a simple MALDI-MS method.

by Takuya Shuo, Naohiko Koshikawa, Daisuke Hoshino, Tomoko Minegishi, Hiroko Ao-Kondo, Masaaki Oyama, Sadanori Sekiya, Shinichi Iwamoto, Koichi Tanaka, Motoharu Seiki
Published 2012-01-01

Membrane-type 4 matrix metalloproteinase (MT4-MMP) modulates water homeostasis in mice.

by Manakan B Srichai, Heloisa Colleta, Leslie Gewin, Linsey Matrisian, Ty W Abel, Naohiko Koshikawa, Motoharu Seiki, Ambra Pozzi, Raymond C Harris, Roy Zent
Published 2011-02-01

Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo.

by María José Blanco, Iván Rodríguez-Martín, Ana I R Learte, Cristina Clemente, María Gregoria Montalvo, Motoharu Seiki, Alicia G Arroyo, Cristina Sánchez-Camacho
Published 2017-01-01

Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock

by Takeharu Sakamoto, Yuya Fukui, Yasumitsu Kondoh, Kaori Honda, Takeshi Shimizu, Toshiro Hara, Tetsuro Hayashi, Yurika Saitoh, Yoshinori Murakami, Jun-ichiro Inoue, Shuichi Kaneko, Hiroyuki Osada, Motoharu Seiki
Published 2021-10-01

Endothelial MT1‐MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis

by Sergio Esteban, Cristina Clemente, Agnieszka Koziol, Pilar Gonzalo, Cristina Rius, Fernando Martínez, Pablo M Linares, María Chaparro, Ana Urzainqui, Vicente Andrés, Motoharu Seiki, Javier P Gisbert, Alicia G Arroyo
Published 2020-02-01

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis

by Cristina Clemente, Cristina Rius, Laura Alonso-Herranz, Mara Martín-Alonso, Ángela Pollán, Emilio Camafeita, Fernando Martínez, Rubén A. Mota, Vanessa Núñez, Cristina Rodríguez, Motoharu Seiki, José Martínez-González, Vicente Andrés, Mercedes Ricote, Alicia G. Arroyo
Published 2018-03-01

Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts

by Ayako Sato, Sei Kakinuma, Masato Miyoshi, Akihide Kamiya, Tomoyuki Tsunoda, Shun Kaneko, Jun Tsuchiya, Taro Shimizu, Eiko Takeichi, Sayuri Nitta, Fukiko Kawai‐Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Naohiko Koshikawa, Motoharu Seiki, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanabe
Published 2020-02-01

New insight into the role of MMP14 in metabolic balance

by Hidetoshi Mori, Ramray Bhat, Alexandre Bruni-Cardoso, Emily I. Chen, Danielle M. Jorgens, Kester Coutinho, Katherine Louie, Benjamin Ben Bowen, Jamie L. Inman, Victoria Tecca, Sarah J. Lee, Sabine Becker-Weimann, Trent Northen, Motoharu Seiki, Alexander D. Borowsky, Manfred Auer, Mina J. Bissell
Published 2016-07-01