Possibility of Polyunsaturated Fatty Acids for the Prevention and Treatment of Neuropsychiatric Illnesses

by Michio Hashimoto, Motoko Maekawa, Masanori Katakura, Kei Hamazaki, Yutaka Matsuoka
Published 2014-01-01

Evaluation of Pax6 mutant rat as a model for autism.

by Toshiko Umeda, Noriko Takashima, Ryoko Nakagawa, Motoko Maekawa, Shiro Ikegami, Takeo Yoshikawa, Kazuto Kobayashi, Kazuo Okanoya, Kaoru Inokuchi, Noriko Osumi
Published 2010-12-01

Genome-wide association study of schizophrenia in Japanese population.

by Kazuo Yamada, Yoshimi Iwayama, Eiji Hattori, Kazuya Iwamoto, Tomoko Toyota, Tetsuo Ohnishi, Hisako Ohba, Motoko Maekawa, Tadafumi Kato, Takeo Yoshikawa
Published 2011-01-01

Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses.

by Motoko Maekawa, Noriko Takashima, Miho Matsumata, Shiro Ikegami, Masanori Kontani, Yoshinobu Hara, Hiroshi Kawashima, Yuji Owada, Yoshinobu Kiso, Takeo Yoshikawa, Kaoru Inokuchi, Noriko Osumi
Published 2009-01-01

Population-specific haplotype association of the postsynaptic density gene DLG4 with schizophrenia, in family-based association studies.

by Shabeesh Balan, Kazuo Yamada, Eiji Hattori, Yoshimi Iwayama, Tomoko Toyota, Tetsuo Ohnishi, Motoko Maekawa, Manabu Toyoshima, Yasuhide Iwata, Katsuaki Suzuki, Mitsuru Kikuchi, Takeo Yoshikawa
Published 2013-01-01

Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.

by Tetsuo Ohnishi, Kazuo Yamada, Akiko Watanabe, Hisako Ohba, Toru Sakaguchi, Yota Honma, Yoshimi Iwayama, Tomoko Toyota, Motoko Maekawa, Kazutada Watanabe, Sevilla D Detera-Wadleigh, Shigeharu Wakana, Takeo Yoshikawa
Published 2011-01-01

Peroxisome proliferator-activated receptor α as a novel therapeutic target for schizophrenia

by Yuina Wada, Motoko Maekawa, Tetsuo Ohnishi, Shabeesh Balan, Shigeru Matsuoka, Kazuya Iwamoto, Yoshimi Iwayama, Hisako Ohba, Akiko Watanabe, Yasuko Hisano, Yayoi Nozaki, Tomoko Toyota, Tomomi Shimogori, Masanari Itokawa, Tetsuyuki Kobayashi, Takeo Yoshikawa
Published 2020-12-01

Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype.

by Akiko Watanabe, Tomoko Toyota, Yuji Owada, Takeshi Hayashi, Yoshimi Iwayama, Miho Matsumata, Yuichi Ishitsuka, Akihiro Nakaya, Motoko Maekawa, Tetsuo Ohnishi, Ryoichi Arai, Katsuyasu Sakurai, Kazuo Yamada, Hisatake Kondo, Kenji Hashimoto, Noriko Osumi, Takeo Yoshikawa
Published 2007-11-01

Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice

by Naoko Morimura, Hiroki Yasuda, Kazuhiko Yamaguchi, Kei-ichi Katayama, Minoru Hatayama, Naoko H. Tomioka, Maya Odagawa, Akiko Kamiya, Yoshimi Iwayama, Motoko Maekawa, Kazuhiko Nakamura, Hideo Matsuzaki, Masatsugu Tsujii, Kazuyuki Yamada, Takeo Yoshikawa, Jun Aruga
Published 2017-06-01

Investigation of betaine as a novel psychotherapeutic for schizophreniaResearch in context

by Tetsuo Ohnishi, Shabeesh Balan, Manabu Toyoshima, Motoko Maekawa, Hisako Ohba, Akiko Watanabe, Yoshimi Iwayama, Yuko Fujita, Yunfei Tan, Yasuko Hisano, Chie Shimamoto-Mitsuyama, Yayoi Nozaki, Kayoko Esaki, Atsuko Nagaoka, Junya Matsumoto, Mizuki Hino, Nobuko Mataga, Akiko Hayashi-Takagi, Kenji Hashimoto, Yasuto Kunii, Akiyoshi Kakita, Hirooki Yabe, Takeo Yoshikawa
Published 2019-07-01

VLDL-specific increases of fatty acids in autism spectrum disorder correlate with social interaction

by Noriyoshi Usui, Keiko Iwata, Taishi Miyachi, Shu Takagai, Keisuke Wakusawa, Takahiro Nara, Kenji J. Tsuchiya, Kaori Matsumoto, Daisuke Kurita, Yosuke Kameno, Tomoyasu Wakuda, Kiyokazu Takebayashi, Yasuhide Iwata, Toru Fujioka, Takaharu Hirai, Manabu Toyoshima, Tetsuo Ohnishi, Tomoko Toyota, Motoko Maekawa, Takeo Yoshikawa, Masato Maekawa, Kazuhiko Nakamura, Masatsugu Tsujii, Toshiro Sugiyama, Norio Mori, Hideo Matsuzaki
Published 2020-08-01

Cooperation of LIM domain‐binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia

by Tetsuo Ohnishi, Yuji Kiyama, Fumiko Arima‐Yoshida, Mitsutaka Kadota, Tomoe Ichikawa, Kazuyuki Yamada, Akiko Watanabe, Hisako Ohba, Kaori Tanaka, Akihiro Nakaya, Yasue Horiuchi, Yoshimi Iwayama, Manabu Toyoshima, Itone Ogawa, Chie Shimamoto‐Mitsuyama, Motoko Maekawa, Shabeesh Balan, Makoto Arai, Mitsuhiro Miyashita, Kazuya Toriumi, Yayoi Nozaki, Rumi Kurokawa, Kazuhiro Suzuki, Akane Yoshikawa, Tomoko Toyota, Toshihiko Hosoya, Hiroyuki Okuno, Haruhiko Bito, Masanari Itokawa, Shigehiro Kuraku, Toshiya Manabe, Takeo Yoshikawa
Published 2021-04-01

Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology

by Masayuki Ide, Tetsuo Ohnishi, Manabu Toyoshima, Shabeesh Balan, Motoko Maekawa, Chie Shimamoto‐Mitsuyama, Yoshimi Iwayama, Hisako Ohba, Akiko Watanabe, Takashi Ishii, Norihiro Shibuya, Yuka Kimura, Yasuko Hisano, Yui Murata, Tomonori Hara, Momo Morikawa, Kenji Hashimoto, Yayoi Nozaki, Tomoko Toyota, Yuina Wada, Yosuke Tanaka, Tadafumi Kato, Akinori Nishi, Shigeyoshi Fujisawa, Hideyuki Okano, Masanari Itokawa, Nobutaka Hirokawa, Yasuto Kunii, Akiyoshi Kakita, Hirooki Yabe, Kazuya Iwamoto, Kohji Meno, Takuya Katagiri, Brian Dean, Kazuhiko Uchida, Hideo Kimura, Takeo Yoshikawa
Published 2019-12-01